Benzodiazepine abuse alone is uncommon. The duration of action is significantly variable between specific drugs, so the course of withdrawal can be very variable. The associations between benzodiazepine abuse and an increased rate of congenital defects cited in older case-controlled studies have not been confirmed in newer reports, and long-term child behavioral deficits have not been reported. Preterm delivery is more likely as with maternal abuse of other drugs. Acute withdrawal can be life threatening, and tapering of drug should incorporate symptom-driven protocols. Anesthetic requirements may be increased in the chronically abusing parturient.
KeywordsAddiction Obstetric anesthesia Benzodiazepine Congenital anomalies
- 2.Substance Abuse and Mental Health Services Administration. Results from the 2013 National Survey on Drug Use and Health: Summary of National Findings. NSDUH Series H-48, HHS Publication No. (SMA) 14-4863. Rockville: Substance Abuse and Mental Health Services Administration; 2014.Google Scholar
- 9.Long LP, Johnson B. Addiction: part I. Benzodiazepines—side effects, abuse risk, and alternatives. Am Fam Physician. 2000;61:2121–8.Google Scholar