von Willebrand Disease

  • James P. R. BrownEmail author
  • Joanne Douglas


This chapter outlines the pathophysiology, clinical presentation, inheritance, subclassification, and incidence of von Willebrand disease. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with von Willebrand disease, including treatment of acute hemorrhage.


von Willebrand disease Inherited bleeding disorder Factor VIII Desmopressin Inherited coagulopathy 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.UBC Department of Anesthesiology, Pharmacology and TherapeuticsBC Women’s HospitalVancouverCanada
  2. 2.Department of AnesthesiaBC Women’s HospitalVancouverCanada

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