von Willebrand Disease
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This chapter outlines the pathophysiology, clinical presentation, inheritance, subclassification, and incidence of von Willebrand disease. The chapter describes the interaction with pregnancy and discusses the medical and anesthetic management of pregnant women with von Willebrand disease, including treatment of acute hemorrhage.
Keywordsvon Willebrand disease Inherited bleeding disorder Factor VIII Desmopressin Inherited coagulopathy
- 3.American Society of Hematology. Quick reference: 2012 clinical practice guideline on the evaluation and management of von Willebrand Disease (VWD). 2012. Adapted from: The diagnosis, evaluation, and management of von Willebrand disease. National Heart, Lung, and Blood Institute, NIH Pub no 08-5832. Dec 2007.Google Scholar
- 6.The Australian Haemophilia Centre Directors’ Organisation. Evidence-based clinical practice guidelines for the use of recombinant and plasma-derived FVIII and FIX products. 2006 National Blood Authority: Australian Health Ministers’ Advisory Council. http://www.ahcdo.org.au/sitebuilder/publications/knowledge/asset/files/1/finalglswithbookmarksjune2006.pdf. Accessed 4 May 2016.