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Tuberous Sclerosis

  • Minxian Liang
  • Jie Zhou
Chapter

Abstract

Tuberous sclerosis (TSC) is a genetic multisystem disorder, demonstrating as multiple benign hamartomas of various organs. The expression of the disease varies, and the affected genes are TSC1 and TSC2, which encode hamartin and tuberin, respectively. Central neural system MRI should be obtained, and other diagnostic testing such as fetal echocardiography should be used based on patients’ situation as well. Anesthetic management of the parturient with TSC may be complicated by different organ involvement, and it should be carefully considered.

Keywords

Tuberous sclerosis Hamartomas Seizure Cardiac rhabdomyomas Anesthetic management 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of AnesthesiologyBrigham and Women’s Hospital, Harvard Medical SchoolBostonUSA

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