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Peripartum Cardiomyopathy

  • Mahesh Vaidyanathan
  • Paloma Toledo
Chapter

Abstract

Peripartum cardiomyopathy (PPCM) is a rare form of cardiomyopathy that develops during the peripartum period in women without preexisting cardiac disease. Patients often initially present with exertional dyspnea or paroxysmal nocturnal dyspnea. The pathophysiology in patients with PPCM is related to diminished cardiac output. Diagnosis is made when echocardiographic evidence of left ventricular systolic dysfunction is identified. An elevated BNP is not diagnostic of PPCM, but elevated BNP levels, above normal pregnancy and postpartum values, have been reported in PPCM. Bromocriptine therapy (2.5 mg BID) has been associated with improved mortality, New York Heart Association (NYHA) status, and ejection fraction in PPCM. However, heart transplant remains a possible requirement for survival.

Keywords

Cardiomyopathy Pregnancy Dyspnea Echocardiography Beta-natriuretic peptide (BNP) Bromocriptine Heart transplant 

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of AnesthesiologyNorthwestern UniversityChicagoUSA

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