Orthotropic Thin Shell Elasticity Estimation for Surface Registration

  • Qingyu Zhao
  • Stephen Pizer
  • Ron Alterovitz
  • Marc Niethammer
  • Julian Rosenman
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 10265)


Elastic physical models have been widely used to regularize deformations in different medical object registration tasks. Traditional approaches usually assume uniform isotropic tissue elasticity (a constant regularization weight) across the whole domain, which contradicts human tissue elasticity being not only inhomogeneous but also anisotropic. We focus on producing more physically realistic deformations for the task of surface registration. We model the surface as an orthotropic elastic thin shell, and we propose a novel statistical framework to estimate inhomogeneous and anisotropic shell elasticity parameters only from a group of known surface deformations. With this framework we show that a joint estimation of within-patient surface deformations and the shell elasticity parameters can improve groupwise registration accuracy. The method is tested in the context of endoscopic reconstruction-surface registration.



This work was supported by NIH grant R01 CA158925. We thank Dr. Bhisham Chera from the Department of Radiation Oncology for providing the endoscopy data.


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Qingyu Zhao
    • 1
  • Stephen Pizer
    • 1
    • 2
  • Ron Alterovitz
    • 1
  • Marc Niethammer
    • 1
  • Julian Rosenman
    • 1
    • 2
  1. 1.Computer ScienceUNC Chapel HillChapel HillUSA
  2. 2.Radiation OncologyUNC Chapel HillChapel HillUSA

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