Closure Methods Following Transsphenoidal Surgery

  • Paul A. GardnerEmail author
  • Carl H. Snyderman
  • Juan C. Fernandez-Miranda
  • Eric W. Wang


Cerebrospinal fluid (CSF) leak is one of the most common postoperative complications following endonasal surgery. The rate varies with defect location, tumor type, reconstruction technique, surgeon experience, and patient factors. CSF leak rates range from 1.5 to 5% for pituitary adenomas to 10 to 16% for craniopharyngiomas and meningiomas. The severity of intraoperative CSF leak also correlates with the risk of postoperative leak. While this relationship is intuitive, classifying the severity can be challenging.


CSF leak Nasoseptal flap Pituitary surgery Sellar reconstruction 

Supplementary material

Video 18.1

Demonstration of surgical technique for elevation of a right nasoseptal flap (MPG 248944 kb)

Video 18.2

Coverage of a sellar defect with a right nasoseptal flap (MP4 1860 kb)


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Paul A. Gardner
    • 1
    Email author
  • Carl H. Snyderman
    • 2
  • Juan C. Fernandez-Miranda
    • 1
  • Eric W. Wang
    • 3
  1. 1.Department of Neurological SurgeryUniversity of Pittsburgh School of MedicinePittsburghUSA
  2. 2.University of Pittsburgh School of MedicineOtolaryngology and Neurological SurgeryPittsburghUSA
  3. 3.University of Pittsburgh School of MedicineOtolaryngologyPittsburghUSA

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