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Peripheral Artery Orbital Atherectomy: Principles and Clinical Applications

  • Vinayak Subramanian
  • Ivy Smith
  • George L. Adams
Chapter

Abstract

Peripheral artery disease (PAD) is characterized by the narrowing of arteries of the extremities. Currently, it affects between 8–12 million Americans and over 200 million people worldwide, and has emerged as a significant global public health concern [1]. The burden of this disease is partly due to the rise in epidemics of diabetes, renal insufficiency, and an aging population, all of which increase the risk of developing vascular disease [2, 3, 4]. The clinical presentation of PAD is broad, ranging from being asymptomatic, increased severity to intermittent claudication with activity, and, at its worst, critical limb ischemia (CLI), which is characterized by rest pain and/or non-healing ulcers. CLI patients often face the morbid prospect of limb amputation due to a non-healing ulceration. Not only do these patients face the prospect of losing their limb but with this they lose their independence and may even lose their life. Patients undergoing amputation have a mortality of 50% at 5 years and 70% at 10 years [5].

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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Vinayak Subramanian
    • 1
  • Ivy Smith
    • 2
  • George L. Adams
    • 3
  1. 1.UNC School of MedicineChapel HillUSA
  2. 2.UNC REX Hospital UNC Health Care SystemRaleighUSA
  3. 3.UNC School of Medicine, Cardiovascular and Peripheral Vascular Research, UNC REX HospitalRaleighUSA

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