Challenges and Optimization of Apheresis Procedures in Resource-Limiting Environments

  • Mickey B. C. KohEmail author
  • Senarath Banda Abeykoon Jayasekara
  • Rajeeka Lakmali Morawakage
Part of the Advances and Controversies in Hematopoietic Transplantation and Cell Therapy book series (ACHTCT)


Apheresis capabilties are increasingly part of the essential infrastructure of national health systems in resource limited countries. It is needed for the maintenance of a safe and sufficient blood supply and is a integral component of the hematopoietic progenitor cell transplant programs. Although there are initial capital costs for starting such a program, there has been confirmation of its cost-effectiveness and importance. Guidelines for stem cell collection and therapeutic apheresis as well as systematic training and qualification of the laboratory have been consistently identified as important areas to focus upon in resource limited countries. Also, highlighted in this chapter are country-specific examples with an overview of the unique challenges and opportunities that exist in setting up a viable apheresis service as well as an in-depth focus on the developmental pathways for achieving this.


Apheresis Hematopoietic cell collection Transplant Resource limited countries 


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Copyright information

© Springer Nature Switzerland AG 2020

Authors and Affiliations

  • Mickey B. C. Koh
    • 1
    • 2
    Email author
  • Senarath Banda Abeykoon Jayasekara
    • 3
  • Rajeeka Lakmali Morawakage
    • 4
  1. 1.Department of HaematologySt George’s University Hospital HospitalsLondonUK
  2. 2.Blood Services GroupHealth Sciences AuthoritySingaporeSingapore
  3. 3.National Blood CentreNational Blood Transfusion Service of Sri LankaColomboSri Lanka
  4. 4.Regional Blood CentreNational Cancer Institute of Sri LankaMaharagamaSri Lanka

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