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Macrophages pp 147–158Cite as

Macrophages in Invertebrates: From Insects and Crustaceans to Marine Bivalves

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Part of the book series: Results and Problems in Cell Differentiation ((RESULTS,volume 62))

Abstract

Macrophages are critical components of the antimicrobial response. The recent explosion of knowledge on the evolutionary, genetic, and biochemical aspects of the interaction between macrophages and microbes has renewed scientific interest in macrophages. The conservation of immune components or mechanisms between organisms during the evolutionary process allows us to elucidate antimicrobial mechanisms or discover new immune functions through the study of basal-branching organisms, such as invertebrates. As a result, immunity in non-vertebrates has attracted the attention of researchers in the last few decades. In this review, we summarize what is presently known about macrophage-like cells in various invertebrate species.

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Abbreviations

PAMPs:

Pathogen-associated molecular patterns

PGRP:

Peptidoglycan recognition protein

PRR:

Pattern recognition receptor

RNS:

Reactive nitrogen species

ROS:

Reactive oxygen species

TEP:

Thioester-containing protein

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Authors and Affiliations

  1. URMITE, CNRS UMR 7278, IRD198, INSERM U1095, APHM, Institut Hospitalier Universitaire Méditerranée-Infection, Aix-Marseille Université, 19-21 Bd Jean Moulin, 13385, Marseille Cedex 05, France

    Prasad Abnave, Xavier Muracciole & Eric Ghigo

  2. Department of Zoology, University of Oxford, Tinbergen Building, South Parks Road, OX1 3PS, Oxford, UK

    Prasad Abnave

  3. Department of Radiotherapy Oncology, CHU La Timone, Assistance Publique-Hopitaux Marseille, Marseille, France

    Xavier Muracciole

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  1. Prasad Abnave
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  2. Xavier Muracciole
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  3. Eric Ghigo
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Correspondence to Eric Ghigo .

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Editors and Affiliations

  1. Department of Surgery, The Houston Methodist Hospital, Houston, Texas, USA

    Malgorzata Kloc

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Abnave, P., Muracciole, X., Ghigo, E. (2017). Macrophages in Invertebrates: From Insects and Crustaceans to Marine Bivalves. In: Kloc, M. (eds) Macrophages. Results and Problems in Cell Differentiation, vol 62. Springer, Cham. https://doi.org/10.1007/978-3-319-54090-0_6

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