Cardiac Magnetic Resonance Elastography

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Abstract

Magnetic resonance elastography (MRE) is a novel, innovative noninvasive imaging technique used to estimate the stiffness of soft tissues. It has been shown that MRE can be used as a research tool to diagnose different disease states in the heart, liver, brain, pancreas, breast, aorta etc. Currently, liver MRE is a clinical tool to stage liver fibrosis. This chapter describes the principle of MRE, the motivation for use of MRE for cardiac applications, and the current state-of-the-art in the development of cardiac MRE, which includes the requirement of hardware, pulse sequences and analysis. Finally, cardiac MRE applications and future directions are also discussed/presented.

Abbreviations

DI

Direct inversion

DTI

Diffusion tensor imaging

ECV

Extra-cellular volume

ED

End-diastole

ES

End-systole

FDA

Food and Drug Administration

GRE

Gradient-recalled echo

HCM

Hypertrophic cardiomyopathy

HF

Heart failure

HFpEF

Heart failure with preserved ejection fraction

HFrEF

Heart failure with reduced ejection fraction

LFE

Local frequency estimation

LV

Left ventricular

MEG

Motion encoding gradient

MI

Myocardial infarction

MRE

Magnetic resonance elastography

MRI

Magnetic resonance imaging

PG

Phase gradient

P-V

Pressure-volume

TE

Echo time

TR

Repetition time

UE

Ultrasound elastography

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Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Department of RadiologyThe Ohio State UniversityColumbusUSA

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