Lymphedema pp 205-219 | Cite as

Cutaneous Manifestations of Edema

Chapter
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Abstract

Edema is an excess of interstitial fluid and is an important sign of ill health in clinical medicine. Edema results from an excess of interstitial fluid when lymph load exceeds lymph drainage for a sustained period of time. When it occurs in peripheral tissues, fluid accumulates predominately in the subcutaneous tissues, but also in the skin. When peripheral edema is caused solely by reduced lymph drainage, it is called lymphedema and produces characteristic clinical signs. This chapter describes these signs, which are often of diagnostic importance.

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Highlighted References

  1. 1.
    Levick JR, Michel CC. Microvascular fluid exchange and the revised Starling principle. Cardiovasc Res. 2010;87(2):198–210.CrossRefPubMedGoogle Scholar
  2. 2.
    Lymphoedema Framework. Best Practice for the Management of Lymphoedema. International Consensus. London: Medical Education; 2006. http://www.lympho.org/mod_turbolead/upload/file/Lympho/Best_practice_20_July.pdf.
  3. 3.
    Thomas KS, Crook AM, Nunn AJ, et al. Penicillin to prevent recurrent leg cellulitis. N Engl J Med. 2013;368(18):1695–703.CrossRefPubMedGoogle Scholar
  4. 4.
    Keppler-Noreuil KM, Sapp JC, Lindhurst MJ, et al. Clinical delineation and natural history of the PIK3CA-related overgrowth spectrum. Am J Med Genet A. 2014;164A(7):1713–33.CrossRefPubMedGoogle Scholar

References

  1. 5.
    Levick JR. An introduction to cardiovascular physiology. 5th ed. London: Arnold; 2010.Google Scholar
  2. 6.
    Stemmer R. Ein klinisches Zeichen zur Früh- und Differentialdiagnose des Lymphödems. Vasa. 1976;5:261–2.PubMedGoogle Scholar
  3. 7.
    Földi E. Über das Stemmer'sche Zeichen. Vasomed. 1997;9:187–9.Google Scholar
  4. 8.
    Stöberl C, Partsch H. Congestive lymphostatic papillomatosis. Hautarzt. 1988;39(7):441–6.PubMedGoogle Scholar
  5. 9.
    Khanna M, Naraghi AM, Salonen D, Bhumbra R, et al. Massive localised lymphoedema: clinical presentation and MR imaging characteristics. Skelet Radiol. 2011;40(5):647–52.CrossRefGoogle Scholar
  6. 10.
    Manduch M, Oliveira AM, Nascimento AG, Folpe AL. Massive localised lymphoedema: a clinicopathological study of 22 cases and review of the literature. J Clin Pathol. 2009;62(9):808–11.CrossRefPubMedGoogle Scholar
  7. 11.
    Ramelet AA, Perrin M, Kern P, Bounameaux H. Phebology. 5th ed. Cedex: Elsevier; 2008.Google Scholar
  8. 12.
    Hirschmann JV, Raugi GJ. Lower limb cellulitis and its mimics: part II. Conditions that simulate lower limb cellulitis. J Am Acad Dermatol. 2012;67(2):177.CrossRefPubMedGoogle Scholar
  9. 13.
    Nutman TB. Lymphatic filariasis. London: Imperial College Press; 2000.CrossRefGoogle Scholar
  10. 14.
    Chira S, Miller LG. Staphylococcus aureus is the most common identified cause of cellulitis: a systemic review. Epidemiol Infect. 2010;138:313–7.CrossRefPubMedGoogle Scholar
  11. 15.
    Lee R, Saardi KM. Schwartz RA lymphedema-related angiogenic tumors and other malignancies. Clin Dermatol. 2014;32(5):616–20.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing AG 2018

Authors and Affiliations

  1. 1.Dermatological MedicineSt George’s University of LondonLondonUK

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