Osteoporosis and Fatigue Fracture Prevention by Analysis of Bone Microdamage

  • Gerardo PresbíteroEmail author
  • David Gutiérrez
  • David Taylor
Conference paper
Part of the The Minerals, Metals & Materials Series book series (MMMS)


We analyzed the conditions under which microcracks, generated by fatigue, affect the fracture properties of bones; this has clinical relevance to stress fractures and osteoporosis. A novel theoretical model was developed to describe microcrack behaviour, using probabilistic analysis and the concept of a characteristic length. In this way we identified effects of aging and gamma radiation sterilisation, which weaken bone and cause accelerated development of microcracks. This work will help in the development of better predictive models to understand and prevent stress fractures and osteoporosis-related fragility fractures.


Osteoporosis Weibull distribution Fatigue fractures Gamma radiation Bone microdamage 


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Copyright information

© The Minerals, Metals & Materials Society 2017

Authors and Affiliations

  • Gerardo Presbítero
    • 1
    Email author
  • David Gutiérrez
    • 2
  • David Taylor
    • 3
  1. 1.Faculty of EngineeringNational Autonomous University of Mexico, University Centre for Advanced Technology (PUNTA-UNAM)MonterreyMexico
  2. 2.Center for Research and Advanced Studies (Cinvestav)MonterreyMexico
  3. 3.Trinity Centre for BioengineeringTrinity College DublinDublinIreland

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