Development of Sponge Structure and Casting Conditions for Absorbable Magnesium Bone Implants
In the case of bone defects, there are two different methods to close such defects. One option is to use bone autografts, but therefore the bone graft has to be cut off from the same person’s hip. In this case the patient has to undergo an additional surgery, which bears complications, like causing inflammations. Absorbable, open-pored implants minimize these risks. Synthetic bone implants are typically made of ceramics, bioglass or polymers. In this study, magnesium alloys were investigated as absorbable porous bone substitute materials in which the bone can grow into. The main advantages are the design flexibility to produce individual implants by investment casting and mechanical properties similar to the bone. In order to adapt the degradation behavior to the bone’s ingrowth behavior, the implant material has to be alloyed and coated. Moreover, to meet the mechanical requirements, finite element simulations of the sponge structure were used during the design phase of the structures and compression tests were conducted for experimental validation.
KeywordsSponge structure Absorbable magnesium Bone implants
This research is sponsored by the German Research Foundation (DFG) within the project “Interfacial effects and ingrowing behavior of magnesium-based foams as bioresorbable bone substitute material” (grant no. MA 1175/52-1).
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