TCI/TIVA Adult Case Studies

  • Nicholas SutcliffeEmail author


Total intravenous anaesthesia (TIVA) has many potential benefits, despite this, in many countries rates of TIVA remain low and education in the technique is lacking. This chapter considers the merits of Target Controlled Infusion (TCI) versus Manual Controlled Infusion (MCI), going on to consider appropriate dosing regimens for both hypnotic and opiate infusions. Detailed case studies are presented of induction and maintenance of general anesthesia and sedation. Appropriate doses in real life clinical scenarios are considered together with supporting evidence from published studies. A consideration of hypnotic/opiate interaction is also presented.


Adults Anaesthesia, intravenous Anaesthetics, intravenous/pharmacokinetics Anaesthetics, intravenous/pharmacodynamics Clinical pharmacology Hypnotics and sedatives/administration and dosage Models, statistical Models, biological Propofol/pharmacokinetics Propofol/pharmacodynamics 

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© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Hamad Medical Corporation, Hamad Medical CityDohaQatar

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