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Grading and Treatment of Acute Graft-Versus-Host Disease

  • Anar MikailovEmail author
  • Molly Plovanich
  • Arturo P. Saavedra
Chapter

Abstract

Acute graft-versus-host disease (aGVHD) remains a major complication and is the leading cause of nonrelapse mortality after allogeneic hematopoietic stem cell transplantation (HSCT). The most commonly involved organ is the skin, providing an opportunity for clinicians to recognize and intervene in this potentially fatal process. Appropriate grading of severity is critical to determine treatment. Therapy for advanced aGVHD is challenging. This chapter reviews the evidence for commonly studied and novel approaches that hold promise.

Keywords

Graft versus Host Disease Acute Graft versus Host Disease GVHD Acute GVHD Acute Cutaneous Graft versus Host Disease Staging Graft versus Host Disease Management Graft versus Host Disease 

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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  • Anar Mikailov
    • 1
    Email author
  • Molly Plovanich
    • 1
  • Arturo P. Saavedra
    • 2
  1. 1.Department of DermatologyBrigham and Women’s Hospital and Harvard Medical SchoolBostonUSA
  2. 2.Department of DermatologyMassachusetts General Hospital and Harvard Medical SchoolBostonUSA

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