Clinical Presentation of Acute Cutaneous Graft-Versus-Host Disease

  • Jonathan A. CotliarEmail author


Acute cutaneous graft-versus-host disease (aGVHD) has a variety of clinical presentations. In the early posttransplantation setting, histologic confirmation of aGVHD via skin biopsy is frequently equivocal. Additional clinical information may be necessary to differentiate aGVHD from its clinical mimickers such as viral exanthema, morbilliform drug eruptions, engraftment syndrome (ES), pre-engraftment syndrome (PES), and in severe cases, Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) [1–3].


Acute graft-versus-host disease aGVHD Hematopoietic stem cell transplantation HSCT 


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Copyright information

© Springer International Publishing AG 2017

Authors and Affiliations

  1. 1.Division of Dermatology, Department of SurgeryCity of Hope National Medical CenterDuarteUSA

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