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Motion-Robust Reconstruction Based on Simultaneous Multi-slice Registration for Diffusion-Weighted MRI of Moving Subjects

  • Bahram Marami
  • Benoit Scherrer
  • Onur Afacan
  • Simon K. Warfield
  • Ali Gholipour
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9902)

Abstract

Simultaneous multi-slice (SMS) echo-planar imaging has had a huge impact on the acceleration and routine use of diffusion-weighted MRI (DWI) in neuroimaging studies in particular the human connectome project; but also holds the potential to facilitate DWI of moving subjects, as proposed by the new technique developed in this paper. We present a novel registration-based motion tracking technique that takes advantage of the multi-plane coverage of the anatomy by simultaneously acquired slices to enable robust reconstruction of neural microstructure from SMS DWI of moving subjects. Our technique constitutes three main components: (1) motion tracking and estimation using SMS registration, (2) detection and rejection of intra-slice motion, and (3) robust reconstruction. Quantitative results from 14 volunteer subject experiments and the analysis of motion-corrupted SMS DWI of 6 children indicate robust reconstruction in the presence of continuous motion and the potential to extend the use of SMS DWI in very challenging populations.

Keywords

Simultaneous multi-slice Diffusion-weighted MRI Motion 

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Copyright information

© Springer International Publishing AG 2016

Authors and Affiliations

  • Bahram Marami
    • 1
  • Benoit Scherrer
    • 1
  • Onur Afacan
    • 1
  • Simon K. Warfield
    • 1
  • Ali Gholipour
    • 1
  1. 1.Boston Children’s HospitalHarvard Medical SchoolBostonUSA

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