Neurophysiological and Behavioral Dysfunctions After Electromagnetic Field Exposure: A Dose Response Relationship

  • Archana Sharma
  • Kavindra Kumar Kesari
  • H. N. Verma
  • Rashmi Sisodia
Part of the Environmental Science and Engineering book series (ESE)


For decades, there has been an increasing concern about the potential hazards of ionizing and non-ionizing radiations on human health. This chapter provides several evidences related to pathophysiology of electromagnetic field (EMF) and its effects on different tissues and organs with special reference to neurophysiological and behavioral dysfunctions. Developing central nervous system (CNS) is extremely sensitive to EMF due to various factors especially due to presence of the high amount of water content, lipids and low amount of antioxidant enzymes. Therefore, the study is focused on the effects of radio frequency (RF) EMF and extremely low frequency magnetic field (ELF MF) on neurological disorders. The severity of effects always depends on exposure doses like, exposure duration, position of subjects, power density and field intensity, which could be measured in terms of specific absorption rate (SAR). There are several biomarkers, which are very useful to measure the radiation effects in both in vitro and in vivo model. The most intensely studied biomarkers by various researchers in CNS are protein kinase C, micronuclei, mitochondrial pathways, melatonin, calcium ion concentration, antioxidant enzymes like glutathione, superoxide dismutase, catalase etc. EMF may also lead to alterations in neurotransmission and consequently in cognitive and memory functions which are mainly linked to the brain hippocampus. Thus there are various histopathological aspects of hippocampus, which are studied and discussed in this chapter. Additionally, the dose response relationship between EMF and biological effects are discussed in this chapter.


Electromagnetic field Antioxidant enzyme Mitochondrial dysfunction CNS 


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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Archana Sharma
    • 1
  • Kavindra Kumar Kesari
    • 2
    • 3
  • H. N. Verma
    • 2
  • Rashmi Sisodia
    • 1
  1. 1.Department of ZoologyUniversity of RajasthanJaipurIndia
  2. 2.Department of Engineering and TechnologyJaipur National UniversityJaipurIndia
  3. 3.Department of Environmental and Biological SciencesUniversity of Eastern FinlandKuopioFinland

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