Volume 103 of the series Progress in the Chemistry of Organic Natural Products pp 37-59


Synthesis of Phytocannabinoids

  • Michael A. SchafrothAffiliated withLaboratorium für Organische Chemie, ETH Zürich Email author 
  • , Erick M. CarreiraAffiliated withLaboratorium für Organische Chemie, ETH Zürich Email author 

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The changing legal landscape including medicinal and recreational consumption of Cannabis sativa has led to renewed interest to study the chemistry and biology of cannabinoids. The chemistry in this chapter highlights approaches to cannabinoid total synthesis with an emphasis on the implementation of modern methods and tactics, which provide access to modified structures and enable investigations of the biology of the cannabinoid product family.


Total synthesis Synthesis Cannabinoids Stereospecific Asymmetric Enantioselective Diastereoselective Tetrahydrocannabinol Conicol Epiconicol Machaeriol Perrottetinene Bisabosqual