Juvenile Angiofibroma and Eye

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Abstract

Juvenile angiofibroma is a rare vascular hamartoma that often occurs in adolescent boys. The continuous growth of tumor can cause bone resorption and destruction of the medial orbital wall, optic canal, chiasmatic–sellar region, clivus, etc. In addition, juvenile angiofibroma may also invade the eye through the inferior orbital fissure. According to the abovementioned reasons, there are a series of eye symptoms and signs among which exophthalmos and ocular dysmotility are common. Optic nerve and chiasma compression result in visual acuity impairment, metamorphopsia, visual field defects, and even blindness. The compressed cavernous sinus could lead to tortuous retinal veins, retinal edema, and palpebral edema. Pressure over oculomotor, trochlear, and abducens nerve could induce paralysis of the corresponding extraocular muscles and presenting as strabismus.

Keywords

Juvenile angiofibroma Orbit Optic nerve Visual acuity Visual field defect 
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References

  1. 1.
    Xu Y, Lin G, Lin C, Fang Z, Li Z, Zhou A, et al. Treatment and prognosis of nasopharyngeal angiofibroma involving the eye and optic nerve. J Laryngol Otol. 2012;126:1108–13.CrossRefPubMedGoogle Scholar
  2. 2.
    Aga A. Juvenile nasopharyngeal angiofibroma presenting as Foster Kennedy Syndrome. Ethiop Med J. 2001;39:251–60.PubMedGoogle Scholar
  3. 3.
    Guoxing Xu, editor. Fundamentals of ophthalmology. New Wun Ching Developmental Publishing Co., Ltd., Taipe; 2008. p. 10–30.Google Scholar
  4. 4.
    Salcone EM, Pepin SM. Intermittent esotropia as the initial presentation of juvenile nasopharyngeal angiofibroma. J AAPOS. 2004;8:201–3.CrossRefPubMedGoogle Scholar
  5. 5.
    Lyons CJ, Tiffin PA, Oystreck D. Acute acquired comitant esotropia: a prospective study. Eye. 1999;13(Pt 5):617–20.CrossRefPubMedGoogle Scholar
  6. 6.
    Zhongfang Z, Zhongyi S. Nasopharyngeal angiofibroma misdiagnosed as optic neuritis in 1 case after the ball. J Clin Otorhinolaryngol. 1999;13:502.Google Scholar
  7. 7.
    Nicolai P, Villaret AB, Farina D, Nadeau S, Yakirevitch A, Berlucchi M, et al. Endoscopic surgery for juvenile angiofibroma: a critical review of indications after 46 cases. Am J Rhinol Allergy. 2010;24:e67–72.CrossRefPubMedGoogle Scholar
  8. 8.
    Midilli R, Karci B, Akyildiz S. Juvenile nasopharyngeal angiofibroma: analysis of 42 cases and important aspects of endoscopic approach. Int J Pediatr Otorhinolaryngol. 2009;73:401–8.CrossRefPubMedGoogle Scholar
  9. 9.
    Bleier BS, Kennedy DW, Palmer JN, Chiu AG, Bloom JD, O’Malley Jr BW. Current management of juvenile nasopharyngeal angiofibroma: a tertiary center experience 1999–2007. Am J Rhinol Allergy. 2009;23:328–30.CrossRefPubMedGoogle Scholar
  10. 10.
    McCombe A, Lund VJ, Howard DJ. Recurrence in juvenile angiofibroma. Rhinology. 1990;28:97–102.PubMedGoogle Scholar
  11. 11.
    Onerci M, Gumus K, Cil B, Eldem B. A rare complication of embolization in juvenile nasopharyngeal angiofibroma. Int J Pediatr Otorhinolaryngol. 2005;69:423–8.CrossRefPubMedGoogle Scholar
  12. 12.
    Finis D, Gumbel H. Central retinal artery occlusion after embolization in juvenile nasopharyngeal angiofibroma. Klin Monbl Augenheilkd. 2009;226:579–80.CrossRefPubMedGoogle Scholar
  13. 13.
    Patrocinio JA, Patrocinio LG, Martins LP, da Cunha AR. Vision recovery following nasopharyngeal angiofibroma excision. Auris Nasus Larynx. 2002;29:309–11.CrossRefPubMedGoogle Scholar
  14. 14.
    Li KK, Lucarelli MJ, Bilyk JR, Joseph MP. Optic nerve decompression for compressive neuropathy secondary to neoplasia. Arch Otolaryngol Head Neck Surg. 1997;123:425–9.CrossRefPubMedGoogle Scholar
  15. 15.
    Lloyd G, Howard D, Phelps P, Cheesman A. Juvenile angiofibroma: the lessons of 20 years of modern imaging. J Laryngol Otol. 1999;113:127–34.PubMedGoogle Scholar
  16. 16.
    Cruz AA, Atique JM, Melo-Filho FV, Elias Jr J. Orbital involvement in juvenile nasopharyngeal angiofibroma: prevalence and treatment. Ophthalmic Plast Reconstr Surg. 2004;20:296–300.CrossRefGoogle Scholar
  17. 17.
    Chang Lin, Zhi-chun Li, Jin-mei Cheng, Gongbiao Lin, Ai-dong Zhou, Yi Zixiang. Nasopharyngeal angiofibroma of pathological features and clinical treatment. Chin J Otolaryngol Head Neck Surg. 2008;43:763–6.Google Scholar
  18. 18.
    Yi ZX, Li ZC, Cheng JM, Zhang R, Lin C, Zhou AD, et al. Huge nasopharyngeal angiofibroma with intracranial extension: change in the dura mater and choice of surgical management. J Laryngol Otol. 2007;121:1108–12.CrossRefPubMedGoogle Scholar
  19. 19.
    Yi Z, Li ZC, Lin C, Ye S. Huge lobulated juvenile angiofibroma: sites of extension and selection of procedures for management. J Otolaryngol. 2003;32:211–6.CrossRefPubMedGoogle Scholar
  20. 20.
    Rong Z, Zixiang Y, Chang L, Guoxing X, Sheng Z, Yuanteng X, et al. Lacrimal hyposecretion: a surgical complication of juvenile nasopharyngeal angiofibroma. Am J Otolaryngol. 2008;29:367–71.CrossRefPubMedGoogle Scholar
  21. 21.
    Hillel AT, Metzinger RC, Nemechek AJ, Nuss DW. Loss of reflex tearing: an expected consequence of juvenile nasopharyngeal angiofibroma. Otolaryngol Head Neck Surg. 2005;133:605–10.CrossRefPubMedGoogle Scholar
  22. 22.
    Lin PY, Cheng CY, Wu CC, Yen MY, Wang SJ, Liao KK, et al. Bilateral neurotrophic keratopathy complicating Vidian neurectomy. Am Ophthalmol. 2001;132:106–8.CrossRefGoogle Scholar
  23. 23.
    Eloy P, Bachy V, Grulois V, Bertrand B. Pyocele of the lachrymal sac: a late and unusual complication after surgery for a juvenile nasopharyngeal angiofibroma. Clin Ophthalmol. 2008;2:211–5.PubMedPubMedCentralGoogle Scholar
  24. 24.
    Fonseca RA, Dantas MA, Kaga T, Spaide RF. Combined hamartoma of the retina and retinal pigment epithelium associated with juvenile nasopharyngeal angiofibroma. Am J Ophthalmol. 2001;132:131–2.CrossRefPubMedGoogle Scholar
  25. 25.
    Hardillo JA, Vander Velden LA, Knegt PP. Denker operation is an effective surgical approach in managing juvenile nasopharyngeal angiofibroma. Ann Otol Rhinol Laryngol. 2004;113:946–50.CrossRefPubMedGoogle Scholar
  26. 26.
    Donald PJ, Enepikedes D, Boggan J. Giant juvenile nasopharyngeal angiofibroma: management by skull-base surgery. Arch Otolaryngol Head Neck Surg. 2004;130:882–6.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  1. 1.Department of Ophthalmology and Otolaryngology–Head & Neck SurgeryFirst Affiliated Hospital of Fujian Medical UniversityFuzhouChina

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