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Embolization of Pediatric Intracranial and Skull Base Vascular Tumors

  • Krishna Amuluru
  • Fawaz Al-Mufti
  • I. Paul Singh
  • Charles J. Prestigiacomo
  • Chirag D. Gandhi
Chapter

Abstract

Neurointerventional embolization has emerged as an important tool in the pre-operative treatment of a variety of pediatric hypervascular intracranial, head, neck, and spinal tumors. The primary goals of preoperative tumor embolization are to reduce intraoperative blood loss, shorten operative time, and decrease surgical morbidity. This technique involves superselective catheterization of the feeding arteries to the tumor bed with infusion of embolic material in order to induce necrosis. Several pediatric intracranial and skull-based tumors may be amenable to preoperative embolization, however each case must be evaluated on an individual basis to achieve the greatest benefit while minimizing potentially dangerous complications. This chapter focuses on indications, techniques and complications of preoperative intracranial and skull-based tumor embolization.

Keywords

Pediatric Brain Tumor Head and Neck Embolization Juvenile Nasal Angiofibroma Choroid Plexus Papilloma Neuroimaging 

References

  1. 1.
    Linabery AM, Ross JA. Trends in childhood cancer incidence in the U.S. (1992–2004). Cancer. 2008;112(2):416–32.CrossRefPubMedGoogle Scholar
  2. 2.
    Ostrom QT, de Blank PM, Kruchko C, Petersen CM, Liao P, Finlay JL, et al. Alex’s Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007–2011. Neuro Oncol. 2015;16 Suppl 10:x1–36.CrossRefPubMedGoogle Scholar
  3. 3.
    Deshmukh VR, Fiorella DJ, McDougall CG, Spetzler RF, Albuquerque FC. Preoperative embolization of central nervous system tumors. Neurosurg Clin N Am. 2005;16(2):411–32, xi.CrossRefPubMedGoogle Scholar
  4. 4.
    Heuer GG, Jackson EM, Magge SN, Storm PB. Surgical management of pediatric brain tumors. Expert Rev Anticancer Ther. 2007;7(12 Suppl):S61–8.CrossRefPubMedGoogle Scholar
  5. 5.
    Brismar J, Cronqvist S. Therapeutic embolization in the external carotid artery region. Acta Radiol Diagn. 1978;19(5):715–31.CrossRefGoogle Scholar
  6. 6.
    Gruber A, Killer M, Mazal P, Bavinzski G, Richling B. Preoperative embolization of intracranial meningiomas: a 17-years single center experience. Minim Invasive Neurosurg. 2000;43(1):18–29.CrossRefPubMedGoogle Scholar
  7. 7.
    Baumgartner JE, Sorenson JM. Meningioma in the pediatric population. J Neurooncol. 1996;29(3):223–8.CrossRefPubMedGoogle Scholar
  8. 8.
    Takeuchi S, Tanaka R, Fujii Y, Abe H, Ito Y. Surgical treatment of hemangioblastomas with presurgical endovascular embolization. Neurol Med Chir. 2001;41(5):246–51; discussion 51–2.CrossRefGoogle Scholar
  9. 9.
    Eskridge JM, McAuliffe W, Harris B, Kim DK, Scott J, Winn HR. Preoperative endovascular embolization of craniospinal hemangioblastomas. AJNR Am J Neuroradiol. 1996;17(3):525–31.PubMedGoogle Scholar
  10. 10.
    Horton JA, Eelkema E, Albright AL. Preoperative embolization of a hemangioblastoma. AJNR Am J Neuroradiol. 1989;10(1):203.PubMedGoogle Scholar
  11. 11.
    Vazquez-Anon V, Botella C, Beltran A, Solera M, Piquer J. Preoperative embolization of solid cervicomedullary junction hemangioblastomas: report of two cases. Neuroradiology. 1997;39(2):86–9.CrossRefPubMedGoogle Scholar
  12. 12.
    Tampieri D, Leblanc R, TerBrugge K. Preoperative embolization of brain and spinal hemangioblastomas. Neurosurgery. 1993;33(3):502–5; discussion 5.CrossRefPubMedGoogle Scholar
  13. 13.
    Sekhar LN, Biswas A, Hallam D, Kim LJ, Douglas J, Ghodke B. Neuroendovascular management of tumors and vascular malformations of the head and neck. Neurosurg Clin N Am. 2009;20(4):453–85.CrossRefPubMedGoogle Scholar
  14. 14.
    Wang HH, Luo CB, Guo WY, Wu HM, Lirng JF, Wong TT, et al. Preoperative embolization of hypervascular pediatric brain tumors: evaluation of technical safety and outcome. Child’s Nerv Sys ChNS Off J Int Soc Pediatric Neurosurg. 2013;29(11):2043–9.CrossRefGoogle Scholar
  15. 15.
    Ashour R, Aziz-Sultan A. Preoperative tumor embolization. Neurosurg Clin N Am. 2014;25(3):607–17.CrossRefPubMedGoogle Scholar
  16. 16.
    Lloyd G, Howard D, Phelps P, Cheesman A. Juvenile angiofibroma: the lessons of 20 years of modern imaging. J Laryngol Otol. 1999;113(2):127–34.CrossRefPubMedGoogle Scholar
  17. 17.
    Haliasos N, Brew S, Robertson F, Hayward R, Thompson D, Chakraborty A. Preoperative embolisation of choroid plexus tumours in children: part I-does the reduction of perioperative blood loss affect the safety of subsequent surgery? Child’s Nerv Sys ChNS Off J Int Soc Pediatric Neurosurg. 2013;29(1):65–70.CrossRefGoogle Scholar
  18. 18.
    Duffis EJ, Gandhi CD, Prestigiacomo CJ, Abruzzo T, Albuquerque F, Bulsara KR, et al. Head, neck, and brain tumor embolization guidelines. J Neurointerventional Surg. 2012;4(4):251–5.CrossRefGoogle Scholar
  19. 19.
    Choi IS, Tantivatana J. Neuroendovascular management of intracranial and spinal tumors. Neurosurg Clin N Am. 2000;11(1):167–85, x.PubMedGoogle Scholar
  20. 20.
    Chewning R, Wyse G, Murphy K. Neurointervention for the peripheral radiologist: tips and tricks. Semin Intervent Radiol. 2008;25(1):42–7.CrossRefPubMedPubMedCentralGoogle Scholar
  21. 21.
    Ahuja A, Gibbons KJ. Endovascular therapy of central nervous system tumors. Neurosurg Clin N Am. 1994;5(3):541–54.PubMedGoogle Scholar
  22. 22.
    Ashour R, Aziz-Sultan MA, Soltanolkotabi M, Schoeneman SE, Alden TD, Hurley MC, et al. Safety and efficacy of onyx embolization for pediatric cranial and spinal vascular lesions and tumors. Neurosurgery. 2012;71(4):773–84.CrossRefPubMedGoogle Scholar
  23. 23.
    Thierry-Chef I, Simon SL, Miller DL. Radiation dose and cancer risk among pediatric patients undergoing interventional neuroradiology procedures. Pediatr Radiol. 2006;36 Suppl 2:159–62.CrossRefPubMedPubMedCentralGoogle Scholar
  24. 24.
    Heran MK, Marshalleck F, Temple M, Grassi CJ, Connolly B, Towbin RB, et al. Joint quality improvement guidelines for pediatric arterial access and arteriography: from the Societies of Interventional Radiology and Pediatric Radiology. J Vasc Inter Radiol JVIR. 2010;21(1):32–43.CrossRefGoogle Scholar
  25. 25.
    Gilad R, Fatterpekar GM, Gandhi CD, Winn HR, Johnson DM, Patel AB, et al. Intracranial tumors: cisternal angle as a measure of midbrain compression for assessing risk of postembolization clinical deterioration. Radiology. 2009;251(3):892–900.CrossRefPubMedGoogle Scholar
  26. 26.
    Vitiello R, McCrindle BW, Nykanen D, Freedom RM, Benson LN. Complications associated with pediatric cardiac catheterization. J Am Coll Cardiol. 1998;32(5):1433–40.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Krishna Amuluru
    • 1
  • Fawaz Al-Mufti
    • 2
  • I. Paul Singh
    • 3
  • Charles J. Prestigiacomo
    • 3
  • Chirag D. Gandhi
    • 3
  1. 1.Department of NeurosurgeryRutgers UniversityNewarkUSA
  2. 2.NeurosurgeryRutgers University-New Jersey Medical SchoolNewarkUSA
  3. 3.Neurological SurgeryRutgers New Jersey Medical SchoolNewarkUSA

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