• Amandeep Singh TaggarEmail author
  • Antonio L. Damato
  • Gil’ad N. Cohen
  • Laszlo Voros
  • Yoshiya Yamada


The word “brachy,” derived from Greek, means short. Brachytherapy is the placement of radioactive sources directly into a tumor. Placing radiation directly into a tumor has several important advantages. Firstly, a highly ablative dose of radiation is delivered within the tumor. Secondly, the inverse-square law, which describes radiation dose at distance from brachytherapy sources, results in tremendous dose differential that can be created within short distances between the tumor and normal tissues. Hence the normal tissue surrounding the tumor is spared from toxic effects of radiation. By placing radiation sources directly into the tumor, there is no need to enlarge the high-dose margin around the tumor to account for uncertainties regarding tumor or patient motion, unlike external beam radiation. In this chapter, we will describe various methods used to deliver brachytherapy treatment and summarize key brachytherapy series to highlight its use in clinical scenarios.


Brachytherapy Low-dose rate Brain Malignant glioma Low-grade glioma Recurrent tumors Spinal brachytherapy 


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Copyright information

© Springer International Publishing AG, part of Springer Nature 2018

Authors and Affiliations

  • Amandeep Singh Taggar
    • 1
    • 2
    Email author
  • Antonio L. Damato
    • 3
  • Gil’ad N. Cohen
    • 3
  • Laszlo Voros
    • 3
  • Yoshiya Yamada
    • 4
  1. 1.Department of Radiation OncologySunnybrook Odette Cancer CenterTorontoCanada
  2. 2.Department of Radiation OncologyUniversity of TorontoTorontoCanada
  3. 3.Department of Medical PhysicsMemorial Sloan Kettering Cancer CenterNew YorkUSA
  4. 4.Department of Radiation OncologyMemorial Sloan Kettering Cancer CenterNew YorkUSA

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