Monash Vision Group’s Gennaris Cortical Implant for Vision Restoration

  • Arthur James Lowery
  • Jeffrey V. Rosenfeld
  • Marcello G. P. Rosa
  • Emma Brunton
  • Ramesh Rajan
  • Collette Mann
  • Mark Armstrong
  • Anand Mohan
  • Horace Josh
  • Lindsay Kleeman
  • Wai Ho Li
  • Jeanette Pritchard
Chapter

Abstract

The Gennaris bionic vision system is a wireless device that has been designed to directly stimulate the primary visual cortex to restore useful vision to people with bilateral, irreversible blindness. Here, we describe the end-to-end system and the design of each component. The rationale for design decisions is provided, including the benefits of cortical stimulation, the need for wireless power and data transmission and the format of the autonomous implant tiles and penetrating micro-electrode arrays. We discuss the broad population of people for which this device may provide benefit, with reference to specific indications of blindness.

Details of laboratory and preclinical tests that we have used to verify the electrical functionality of the device are described. A description of the surgical method that has been developed for implanting tiles in the visual cortex is provided, which will be used to demonstrate proof-of-concept of the system in first-in-human studies. Highlighted is the importance of post-surgical device calibration, psychophysics testing and training of recipients in using the system in both controlled and unsupervised environments. Signal processing algorithms that have been developed to enhance the user experience are described and details provided of how these have been tested to optimise their integration into the full system. Finally, we describe how the Gennaris technology can be applied to a broad spectrum of other technological and health-related challenges.

Keywords

Cortical stimulation Bionic vision Wireless link Implant tile Hermetic Penetrating electrodes Annulus Neurosurgery Neural plasticity Academic-industry partnership 

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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Arthur James Lowery
    • 1
  • Jeffrey V. Rosenfeld
    • 2
  • Marcello G. P. Rosa
    • 3
  • Emma Brunton
    • 1
  • Ramesh Rajan
    • 4
  • Collette Mann
    • 1
  • Mark Armstrong
    • 5
  • Anand Mohan
    • 1
  • Horace Josh
    • 1
  • Lindsay Kleeman
    • 1
  • Wai Ho Li
    • 1
  • Jeanette Pritchard
    • 1
  1. 1.Department of Electrical and Computer Systems EngineeringMonash UniversityClaytonAustralia
  2. 2.Monash Institute of Medical EngineeringMonash UniversityClaytonAustralia
  3. 3.Department of Physiology, Monash Vision Group, Australian Research Council Centre of Excellence for Integrative Brain FunctionMonash UniversityClaytonAustralia
  4. 4.Department of Physiology, Neuroscience Program, Biomedicine Discovery InstituteMonash UniversityClaytonAustralia
  5. 5.Department of DesignMonash Art Design and ArchitectureCaulfieldAustralia

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