The Nucleus

  • Anders Rehfeld
  • Malin Nylander
  • Kirstine Karnov
Chapter

Abstract

The nucleus is the largest organelle in the cell. It contains the nuclear DNA, the main part of the genome, and one to several nucleoli. During cell division, the nuclear DNA is replicated and split into the nuclei of two new daughter cells. The two types of cell divisions, mitosis and meiosis, are explained in detailed yet simple manner. The various types of cell death are also described.

Keywords

Nucleus Nuclear envelope Nuclear lamina Nuclear pore Nucleoplasm Chromatin Heterochromatin Euchromatin Nucleosomes Epigenetic marks Nucleolus Somatic cells Germ cells Cell cycle Interphase Mitosis Meiosis DNA recombination Cell death Apoptosis Necrosis 

References

  1. 1.
    Alberts B. Essential cell biology. 4th ed.Google Scholar
  2. 5.
    Brüel A, Christensen EI, Geneser F, Tranum-Jensen J, Qvortrup K. Genesers Histologi. 1st ed. Munksgaard; 2012.Google Scholar
  3. 19.
    Kumar R, Ghyselinck N, Ishiguro K‐i, Watanabe Y, Kouznetsova A, Höög C, Strong E, Schimenti J, Daniel K, Toth A, de Massy B. MEI4 – a central player in the regulation of meiotic DNA double−strand break formation in the mouse. J Cell Sci. 2015;128:1800–11. doi: 10.1242/jcs.165464.CrossRefPubMedPubMedCentralGoogle Scholar
  4. 24.
    McMahill MS, Sham CW, Bishop DK. Synthesis-dependent strand annealing in meiosis. PLoS Biol. 2007;5(11):e299.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 33.
    Rehfeld A, Nylander M, Karnov KKS. Histologikompendium. 2nd ed. Munksgaard; 2013.Google Scholar
  6. 34.
    Ross MH, Pawlina W. Histology: a text and atlas: with correlated cell and molecular biology. 7th ed. Wolter Kluwer; 2015.Google Scholar
  7. 38.
    Sasaki H, Matsui Y. Epigenetic events in mammalian germ-cell development: reprogramming and beyond. Nat Rev Genet. 2008;9(2):129–40. doi: 10.1038/nrg2295.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Anders Rehfeld
    • 1
  • Malin Nylander
    • 1
  • Kirstine Karnov
    • 1
  1. 1.Faculty of Health and Medical SciencesUniversity of CopenhagenCopenhagenDenmark

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