Acute Respiratory Distress Syndrome (ARDS): Definition, Incidence, and Outcome

  • Rémi Coudroy
  • Florence Boissier
  • Arnaud W. ThilleEmail author


The definition of ARDS has considerably evolved over the last 50 years and is still challenging. Using the current Berlin definition, more than 10% of the patients admitted in the ICU and more than 20% of the patients under mechanical ventilation meet clinical criteria for ARDS. Several RCTs have found a reduction of mortality over the last 15 years using protective ventilation with low tidal volumes and high PEEP levels, and using neuromuscular blockers and prone positioning. However, a large international survey recently highlighted that adherence to this “protective bundle” in the real life has remained far from optimal despite improvement over the last years. Hence, negative outcomes of ARDS patients have hardly decreased in the last decade, and survivors still have a markedly altered quality of life.


Idiopathic Pulmonary Fibrosis Acute Respiratory Distress Syndrome Acute Respiratory Distress Syndrome Patient Peep Level Diffuse Alveolar Damage 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • Rémi Coudroy
    • 1
    • 2
  • Florence Boissier
    • 1
    • 2
  • Arnaud W. Thille
    • 1
    • 2
    • 3
    Email author
  1. 1.CHU de Poitiers, Réanimation MédicalePoitiersFrance
  2. 2.INSERM CIC 1402 (ALIVE Group)Université de Poitiers, Faculté de MédecinePoitiersFrance
  3. 3.Réanimation Médicale, CHU de PoitiersPoitiers CedexFrance

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