Rapid Generation of Structured Physical Phantoms for Mammography and Digital Breast Tomosynthesis

Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9699)

Abstract

Nonuniform phantoms are needed in order to fully characterize the impact of anatomical structures on system performance in mammography and digital breast tomosynthesis (DBT). In this work, a new type of textured physical phantom is presented, compatible for use in both 2D and 3D applications. The breast phantom was first modeled analytically, and then fabricated using inkjet printing onto parchment paper and slide transparencies. A radiographic ink solution was synthesized with 350 mg/mL iohexol and pigmented ink. The effective linear attenuation coefficient (µeff) of the parchment paper alone (0.078 ± 0.003 mm−1) was found to be very close to that of a 70 % adipose, 30 % fibroglandular tissue mixture (0.078 ± 0.004 mm−1). The µeff of the parchment paper with iodine (0.010 ± 0.005 mm−1) was close to that of 100 % fibroglandular tissue (0.11 ± 0.004 mm−1). This new parchment and iodine phantom has strong potential for use in imaging studies.

Keywords

Breast phantom Anthropomorphic Iodine Linear attenuation 

References

  1. 1.
    McLelland, R., Hendrick, R.E., Zinninger, M.D., Wilcox, P.A.: The American college of radiology mammography accreditation program. AJR Am. J. Roentgenol. 157, 473–479 (1991)CrossRefGoogle Scholar
  2. 2.
    Thijssen, M.A.O., Bijkerk, K.R., Van der Burght, R.J.M.: Manual contrast-detail phantom Artinis CDMAM type 3.4. University Medical Center Nijmegen, Department of Radiology, The Netherlands, Utilisation Manual 2006 (2007)Google Scholar
  3. 3.
    Carton, A.K., Bakic, P., Ullberg, C., Derand, H., Maidment, A.D.: Development of a physical 3D anthropomorphic breast phantom. Med. Phys. 38, 891–896 (2011)CrossRefGoogle Scholar
  4. 4.
    Gang, G., Tward, D., Lee, J., Siewerdsen, J.: Anatomical background and generalized detectability in tomosynthesis and cone-beam CT. Med. Phys. 37, 1948–1965 (2010)CrossRefGoogle Scholar
  5. 5.
    Freed, M., Badal, A., Jennings, R.J., de las Heras, H., Myers, K.J., Badano, A.: X-ray properties of an anthropomorphic breast phantom for MRI and x-ray imaging. Phys. Med. Biol. 56, 3513 (2011)Google Scholar
  6. 6.
    Kiarashi, N., Nolte, A.C., Sturgeon, G.M., Segars, W.P., Ghate, S.V., Nolte, L.W., Samei, E., Lo, J.Y.: Development of realistic physical breast phantoms matched to virtual breast phantoms based on human subject data. Med. Phys. 42, 4116–4126 (2015)CrossRefGoogle Scholar
  7. 7.
    Graff, C.G.: A new open-source multi-modality digital breast phantom. In: Medical Imaging 2016: Physics of Medical Imaging. Proceedings of SPIE, vol. 9783 (2016). doi:10.1117/12.2216312

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Lynda Ikejimba
    • 1
  • Christian Graff
    • 1
  • Stephen Glick
    • 1
  1. 1.Division of Imaging, Diagnostics, and Software ReliabilityOSEL/CDRH/FDASilver SpringUSA

Personalised recommendations