Assessment of the Functional Ovarian Reserve
The ovarian reserve is composed of primordial and resting follicles. The number of primordial follicles is determined during early fetal life and declines until menopause. The number of antral follicles reflects the size of primordial follicle pool . Follicles destined to ovulate grow from primordial follicles through the accumulation of fluid in the antral cavity and the proliferation of granulosa and theca interna cells until it reaches the diameter of 2 mm. After the antral follicles reach 2 mm in diameter, they become highly sensitive and responsive to follicle-stimulating hormone (FSH). Follicles in diameter of 2–5 mm constitute a pool of follicles of which one follicle destined to ovulate is selected and finally undergoes ovulation [2, 3]. Those follicles constitute the functional ovarian reserve .
KeywordsAssisted Reproductive Technology Ovarian Reserve Antral Follicle Primordial Follicle Antral Follicle Count
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