MicroRNAs and Hepatocellular Carcinoma

  • Aldo CavalliniEmail author
Part of the Current Clinical Oncology book series (CCO)


Genomic studies have demonstrated that many portions of the human genome do not encode conventional protein-coding genes, but encode biologically active noncoding RNA species. One class of such small noncoding RNA is microRNA (miRNA), comprised of a group of well-conserved, small RNA molecules (21-23 nucleotides) that can up- or down-regulate gene expression in normal and abnormal cellular activities by base pairing with 3′ untranslated regions (3′ UTRs) of target messenger RNA (mRNA) [1].


miRNA Expression Acute Rejection Orthotopic Liver Transplantation miRNA Profile miRNA Expression Pattern 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



Adenoviral vector


ADAM metallopeptidase domain 9




Allograft transplantation


Anti-miRNA antisense oligomer


Carcinoembryonic antigen


DiGeorge syndrome chromosomal region 8


Ribonuclease III


Double-stranded-RNA-binding protein




Ischemic-type biliary lesions


Liver transplantation




RNA messenger


Orthotopic liver transplantation


miRNA with oncogene role


Operational tolerance


Preliminary miRNA


Primary miRNA


Multiprotein RNA induced-silencing complex


RNA-mediated interference


Small interfering RNA


Small noncoding RNA


Transcatheter arterial chemoembolization

TS miR

Tumor Suppressor miRNA


Untranslated region


Exportin 5




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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Laboratory of Cellular and Molecular Biology, Dept. Clinical PathologyIRCCS, Saverio de BellisCastellana GrotteItaly

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