Drug-Induced Sedation Endoscopy (DISE)

  • Aldo Campanini
  • Bhik Kotecha
  • Erica R. Thaler


In this chapter, the authors review the history of drug-induced sedation endoscopy (DISE), and important literature contributions to date regarding its utility in diagnosis of OSA, particularly with regard to assessment of surgical candidacy. Each author also describes his or her own institutional experience, technique, and relevant findings regarding DISE.


DISE Sleep endoscopy Propofol Collapse 


  1. 1.
    Kushida CA, Littner MR, Morgenthaler T, et al. Practice parameters for the indications for polysomnography and related procedures: an update for 2005. Sleep. 2005;28:499–521.PubMedGoogle Scholar
  2. 2.
    Croft CB, Pringle M. Sleep nasendoscopy: a technique of assessment in snoring and obstructive sleep apnoea. Clin Otolaryngol Allied Sci. 1991;16:504–9.CrossRefPubMedGoogle Scholar
  3. 3.
    De Vito A, Carrasco Llatas M, Agnoletti V, et al. European position paper on drug-induced sedation endoscopy (DISE). Sleep Breath. 2014;18(3):453–65.CrossRefPubMedGoogle Scholar
  4. 4.
    Ravesloot MJL, de Vries N. One hundred consecutive patients undergoing drug-induced sleep endoscopy: results and evaluation. Laryngoscope. 2011;121:2710–6.CrossRefPubMedGoogle Scholar
  5. 5.
    Kotecha BT, Hannan AS, Khalil HMB, et al. Sleep nasendoscopy: a 10 year retrospective audit study. Eur Arch Otorhinolaryngol. 2007;264:1361–7.CrossRefPubMedGoogle Scholar
  6. 6.
    Kezirian EJ. Nonresponders to pharyngeal surgery for obstructive sleep apnea: insights from drug-induced sleep endoscopy. Laryngoscope. 2011;121(6):1320–6.CrossRefPubMedPubMedCentralGoogle Scholar
  7. 7.
    Vicini C, De Vito A, Benazzo M, Frassineti S, Campanini A, Frasconi P, Mira E. The nose oropharynx hypopharynx and larynx (NOHL) classification: a new system of diagnostic standardized examination for OSAHS patients. Eur Arch Otorhinolaryngol. 2012;269(4):1297–300.CrossRefPubMedGoogle Scholar
  8. 8.
    Kezirian EJ, Hohenhorst W, de Vries N. Drug-induced sleep endoscopy: the VOTE classification. Eur Arch Otorhinolaryngol. 2011;268(8):1233–6. doi: 10.1007/s00405-011-1633-8 [Epub 2011 May 26].CrossRefPubMedGoogle Scholar
  9. 9.
    Mandel JE, Sarraf E. The variability of response to propofol is reduced when a clinical observation is incorporated in the control: a simulation study. Anesth Analg. 2012;114(6):1221–9.CrossRefPubMedGoogle Scholar
  10. 10.
    Borek RC, Thaler ER, Kim C, Jackson N, Mandel JE, Schwab RJ. Quantitative airway analysis during drug-induced sleep endoscopy for evaluation of sleep apnea. Laryngoscope. 2012;122(11):2592–9.CrossRefPubMedGoogle Scholar
  11. 11.
    De Vito A, Agnoletti V, Berrettini S, et al. Drug-induced sleep endoscopy: conventional versus target controlled infusion techniques—a randomized controlled study. Eur Arch Otorhinolaryngol. 2011;268(3):457–62.CrossRefPubMedGoogle Scholar
  12. 12.
    Campanini A, Canzi P, De Vito A, et al. Awake versus sleep endoscopy: personal experience in 250 OSAHS patients. Acta Otorhinolaryngol Ital. 2010;30(2):73–7.PubMedPubMedCentralGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Aldo Campanini
    • 1
    • 2
  • Bhik Kotecha
    • 3
  • Erica R. Thaler
    • 4
  1. 1.Head and Neck Department—ENT & Oral Surgery UnitG.B. Morgagni—L. Pierantoni Hospital, ASL of RomagnaForlìItaly
  2. 2.Infermi Hospital, ASL of RomagnaFaenzaItaly
  3. 3.Royal National Throat, Nose & Ear HospitalLondonUK
  4. 4.Division of General Otolaryngology, Head and Neck Surgery, Department of Otolaryngology-Head and Neck SurgeryUniversity of Pennsylvania School of MedicinePhiladelphiaUSA

Personalised recommendations