Antibiotic Strategy and Stewardship
Antibiotic stewardship is the optimization of antibiotic regimens to ensure the best treatment selection for individual patients with minimization of side effects and cost while attempting to limit the development of resistance (MacDougall and Polk, Clin Microbiol Rev 18(4):638–656, 2005; Luyt et al., 1–12, 2014). Comprehensive antibiotic management strategies may use a variety of methods to limit antibiotic use in volume, duration, and spectrum. These strategies should also include multidisciplinary efforts to monitor compliance with clinical practice guidelines, policies, and protocols. Formulary restriction, antibiotic cycling, selective reporting of culture susceptibilities, and decision support tools to aid in drug selection are among the means by which antimicrobial use can be directed. Equally important in the critical care setting is the prevention and treatment of nosocomial infections common to critically ill patients.
KeywordsAntibiotic stewardship Nosocomial infections Infection prevention
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