Accuracy Assessment of CBCT-Based Volumetric Brain Shift Field

  • Iris Smit-Ockeloen
  • Daniel Ruijters
  • Marcel Breeuwer
  • Drazenko Babic
  • Olivier Brina
  • Vitor Mendes Pereira
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9401)


The displacement of the brain parenchyma during open brain surgery, known as ‘brain shift’, affects the applicability of pre-operative planning and affects the outcome of the surgery. In this article we investigated the accuracy of a novel method to intra-operatively determine the brain shift displacement field throughout the whole brain volume. The brain shift displacement was determined by acquiring contrast enhanced cone-beam CT before and during the surgery. The respective datasets were pre-processed, landmark enhanced, and elastically registered to find the displacement field. The accuracy of this method was evaluated by artificially creating post-operative data with a known ground truth deformation. The artificial post-operative data was obtained by applying the deformation field from one patient on the pre-operative data of another patient, which was repeated for three patients. The mean error that was found with this method ranged from 1 to 2 mm, while the standard deviation was about 1 mm.


Brain shift Open brain surgery Craniotomy Cone-beam CT Elastic registration 


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Iris Smit-Ockeloen
    • 1
  • Daniel Ruijters
    • 2
  • Marcel Breeuwer
    • 1
    • 2
  • Drazenko Babic
    • 2
  • Olivier Brina
    • 3
  • Vitor Mendes Pereira
    • 3
    • 4
  1. 1.Department of Biomedical EngineeringEindhoven University of TechnologyEindhovenThe Netherlands
  2. 2.Philips HealthcareBestThe Netherlands
  3. 3.Division of Neuroradiology, Department of Medical ImagingUniversity Hospitals of GenevaGenevaSwitzerland
  4. 4.Division of Neuroradiology, Department of Medical Imaging and Division of Neurosurgery, Department of Surgery, Toronto Western HospitalUniversity Health NetworkTorontoCanada

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