Bioimage Informatics for Big Data

  • Hanchuan PengEmail author
  • Jie Zhou
  • Zhi Zhou
  • Alessandro Bria
  • Yujie Li
  • Dean Mark Kleissas
  • Nathan G. Drenkow
  • Brian Long
  • Xiaoxiao Liu
  • Hanbo Chen
Part of the Advances in Anatomy, Embryology and Cell Biology book series (ADVSANAT, volume 219)


Bioimage informatics is a field wherein high-throughput image informatics methods are used to solve challenging scientific problems related to biology and medicine. When the image datasets become larger and more complicated, many conventional image analysis approaches are no longer applicable. Here, we discuss two critical challenges of large-scale bioimage informatics applications, namely, data accessibility and adaptive data analysis. We highlight case studies to show that these challenges can be tackled based on distributed image computing as well as machine learning of image examples in a multidimensional environment.


Howard Hughes Medical Institute Virtual Finger Multiple Imaging Modality Open Microscopy Environment Large Image Dataset 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Hanchuan Peng
    • 1
    Email author
  • Jie Zhou
    • 2
  • Zhi Zhou
    • 1
  • Alessandro Bria
    • 3
    • 4
  • Yujie Li
    • 1
    • 5
  • Dean Mark Kleissas
    • 6
  • Nathan G. Drenkow
    • 6
  • Brian Long
    • 1
  • Xiaoxiao Liu
    • 1
  • Hanbo Chen
    • 1
    • 5
  1. 1.Allen Institute for Brain ScienceSeattleUSA
  2. 2.Department of Computer ScienceNorthern Illinois UniversityDekalbUSA
  3. 3.Department of EngineeringUniversity Campus Bio-Medico of RomeRomeItaly
  4. 4.Department of Electrical and Information EngineeringUniversity of Cassino and L.M.CassinoItaly
  5. 5.Department of Computer ScienceUniversity of GeorgiaAthensUSA
  6. 6.Johns Hopkins University Applied Physics LaboratoryLaurelUSA

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