Generalized Wishart Processes for Interpolation Over Diffusion Tensor Fields

  • Hernán Darío Vargas CardonaEmail author
  • Mauricio A. Álvarez
  • Álvaro A. Orozco
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9475)


Diffusion Magnetic Resonance Imaging (dMRI) is a non-invasive tool for watching the microstructure of fibrous nerve and muscle tissue. From dMRI, it is possible to estimate 2-rank diffusion tensors imaging (DTI) fields, that are widely used in clinical applications: tissue segmentation, fiber tractography, brain atlas construction, brain conductivity models, among others. Due to hardware limitations of MRI scanners, DTI has the difficult compromise between spatial resolution and signal noise ratio (SNR) during acquisition. For this reason, the data are often acquired with very low resolution. To enhance DTI data resolution, interpolation provides an interesting software solution. The aim of this work is to develop a methodology for DTI interpolation that enhance the spatial resolution of DTI fields. We assume that a DTI field follows a recently introduced stochastic process known as a generalized Wishart process (GWP), which we use as a prior over the diffusion tensor field. For posterior inference, we use Markov Chain Monte Carlo methods. We perform experiments in toy and real data. Results of GWP outperform other methods in the literature, when compared in different validation protocols.


Apparent Diffusivity Coefficient Diffusion Tensor Imaging Diffusion Tensor Tensor Field Markov Chain Monte Carlo Method 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.



H.D. Vargas Cardona is funded by Colciencias under the program: formación de alto nivel para la ciencia, la tecnología y la innovación - Convocatoria 617 de 2013. This research has been developed under the project financed by Colciencias with code 1110-657-40687.


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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Hernán Darío Vargas Cardona
    • 1
    Email author
  • Mauricio A. Álvarez
    • 1
  • Álvaro A. Orozco
    • 1
  1. 1.Faculty of EngineeringUniversidad Tecnológica de PereiraPereiraColombia

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