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A Cancer Dynamics Model for an Intermittent Treatment Involving Reduction of Tumor Size and Rise of Growth Rate

  • Virginia Giorno
  • Serena SpinaEmail author
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9520)

Abstract

We propose a model of tumor dynamics based on the Gompertz deterministic law influenced by jumps that occur at equidistant time instants. This model consents to study the effect of a therapeutic program that provides intermittent suppression of cancer cells. In this context a jump represents an application of the therapy that shifts the cancer mass to a fixed level and it produces a deleterious effect on the organism by increasing the growth rate of the cancer cells. The objective of the present study is to provide an efficient criterion to choose the instants in which to apply the therapy by maximizing the time in which the cancer mass is under a fixed control threshold.

Keywords

Therapeutic Application Efficient Criterion Therapeutic Program Intermittent Treatment Control Threshold 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  1. 1.Dipartimento di Studi e Ricerche Aziendali (Management and Information Technology)Università di SalernoFiscianoItaly
  2. 2.Dipartimento di MatematicaUniversità di SalernoFiscianoItaly

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