Embryological Basis of Congenital Anomalies
The normal developmental processes hold the key to our understanding of the biological basis of congenital anomalies. It is remarkable to note how a single fertilized cell, the zygote, undergoes sequential cell divisions followed by coordinated cell proliferation, migration and differentiation, to create something as intricately complex as a human foetus . Interestingly, the various stages of the human embryonic development (see Table 6.1) share homologous developmental trajectories with other vertebrates .
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