From Neural Plate to Neural Tube

  • Rudolf Nieuwenhuys
  • Luis Puelles


The transformation of the neural plate into the neural tube is known as neurulation. During this process, the bilateral outer borders of the neural plate fuse together point-to-point along the median line, forming the roof plate. The neural crest population is released into the mesenchyme at the same time, and the skin also fuses, covering the whole.


Neural Tube Neural Plate Closure Dorsal Basal Blue Neural Stage 
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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  1. 1.Netherlands Institute for NeuroscienceRoyal NL Academy of Arts and SciencesAmsterdamThe Netherlands
  2. 2.Department of Human Anatomy and PsychobiologyUniversity of MurciaMurciaSpain

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