Vascular System

  • M. Elizabeth Oates
  • Vincent L. Sorrell


Knowledge of the injection site and the adequacy of the injection are helpful at the time of image interpretation. Extravasation of radiopharmaceutical can result in an incomplete intravascular injection which, in turn, can lead to a false-negative interpretation of SPECT MPI. Lymphatic uptake and deposition within regional lymph nodes (usually axillary) can occur after a significant extravasation. Implanted IV ports or central venous catheters can be used for radiopharmaceutical administration and can be a source of “hot” artifacts on the final images even if well-flushed.


Central Venous Catheter Lymph Node Basin Regional Lymph Node Basin Nuclear Stress Test Scatter Artifact 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

330381_1_En_14_MOESM1_ESM.avi (23.1 mb)
Fig. 14.1a (AVI 23700 kb)
330381_1_En_14_MOESM2_ESM.mp4 (2.1 mb)
Fig. 14.1b (MP4 2135 kb)
330381_1_En_14_MOESM3_ESM.avi (52.4 mb)
Fig. 14.1c (AVI 53671 kb)
330381_1_En_14_MOESM4_ESM.mp4 (3.1 mb)
Fig. 14.1d (MP4 3126 kb)
Fig. 14.1e

(AVI 85072 kb)

330381_1_En_14_MOESM6_ESM.avi (13.7 mb)
Fig. 14.2a (AVI 14063 kb)
330381_1_En_14_MOESM7_ESM.avi (13.7 mb)
Fig. 14.2b (AVI 14063 kb)


  1. Aras T, Ergun EL, Bozkurt MF. Visualization of the pulmonary artery on 99m Tc-MIBI myocardial perfusion scintigraphy: a cause for focal uptake in the lung. Semin Nucl Med. 2003;33(4):338–41.CrossRefPubMedGoogle Scholar
  2. Burrell S, MacDonald A. Artifacts and pitfalls in myocardial perfusion imaging. J Nucl Med Technol. 2006;34:193–211.PubMedGoogle Scholar
  3. Chamarthy M, Travin MI. Altered biodistribution and incidental findings on myocardial perfusion imaging. Semin Nucl Med. 2010;40:257–70.CrossRefPubMedGoogle Scholar
  4. Gedik GK, Ergun EL, Aslan M, Caner B. Unusual extracardiac findings detected on myocardial perfusion single photon emission computed tomography studies with Tc-99m sestamibi. Clin Nucl Med. 2007;32:920–6.CrossRefPubMedGoogle Scholar
  5. Gentili A, Miron SD, Adler LP. Review of some common artifacts in nuclear medicine. Clin Nucl Med. 1994;19:138–43.CrossRefPubMedGoogle Scholar
  6. Howarth DM, Forstrom LA, O’Connor MK, Thomas PA, Cardew AP. Patient-related pitfalls and artifacts in nuclear medicine imaging. Semin Nucl Med. 1996;26:295–307.CrossRefPubMedGoogle Scholar
  7. Shih WJ, Kiefer V, Gross K, Wierzbinski B, Collins J, Pulmano C, Ryo YU. Intrathoracic and intra-abdominal Tl-201 abnormalities seen on rotating raw cine data on dual radionuclide myocardial perfusion and gated SPECT. Clin Nucl Med. 2002;27:40–4.CrossRefPubMedGoogle Scholar
  8. Strauss HW, Miller DD, Wittry MD, Cerqueira ME, Garcia EV, Iskandrian AS, Schelbert HR, Wackers FJ, Balon HR, Lang O, Machac J. Procedure guideline for myocardial perfusion imaging 3.3 (2008). J Nucl Med Technol. 2008;36:155–61. Accessed 8 June 2015.CrossRefPubMedGoogle Scholar
  9. Tallaj JA, Iskandrian AE. Extracardiac localization of technetium-99m sestamibi. J Nucl Cardiol. 2000;7:789–90.Google Scholar

Copyright information

© Springer International Publishing Switzerland 2017

Authors and Affiliations

  • M. Elizabeth Oates
    • 1
  • Vincent L. Sorrell
    • 2
  1. 1.Division of Nuclear Medicine and Molecular Imaging Department of RadiologyUniversity of KentuckyLexingtonUSA
  2. 2.Division of Cardiovascular Medicine Department of Internal Medicine Gill Heart InstituteUniversity of KentuckyLexingtonUSA

Personalised recommendations