Abstract
Magnetic resonance imaging (MRI) is a non-radiation based examination method, which gains an increasing popularity in research and clinical settings. Manual analysis of large data volumes is a very time-consuming and tedious process. Therefore, automatic analysis methods are required. This paper reviews different methods that have been recently proposed for automatic and semi-automatic lung segmentation from magnetic resonance imaging data. These techniques include thresholding, region growing, morphological operations, active contours, level sets, and neural networks. We also discuss the methodologies that have been utilized for performance and accuracy evaluation of each method.
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References
Abdou, I.E., Pratt, W.K.: Quantitative design and evaluation of enhancement/thresholding edge detectors. Proc. IEEE 67(5), 753–763 (1979)
Armato, S.G., MacMahon, H.: Automated lung segmentation and computer-aided diagnosis for thoracic ct scans. Int. Congr. Ser. 1256, 977–982 (2003)
Avants, B.B., Tustison, N., Song, G.: Advanced normalization tools (ANTs). Insight J. 2, 1–35 (2009)
Avants, B.B., Tustison, N.J., Song, G., Cook, P.A., Klein, A., Gee, J.C.: A reproducible evaluation of ants similarity metric performance in brain image registration. Neuroimage 54(3), 2033–2044 (2011)
Biederer, J., Hintze, C., Fabel, M., Jakob, P., Horger, W., Graessner, J., Bolster, B., Heller, M.: MRI of the lung—ready … get set … go. Magnetom Flash 46, 6–15 (2011)
Biederer, J., Beer, M., Hirsch, W., Wild, J., Fabel, M., Puderbach, M., Van Beek, E.: MRI of the lung (2/3). why … when … how? Insights Imaging 3(4), 355–371 (2012)
Boettger, T., Kunert, T., Meinzer, H.P., Wolf, I.: Interactive constraints for 3d-simplex meshes. In: Proceedings of SPIE Medical Imaging 2005. Image Processing, vol. 5747, pp. 1692–1702. International Society for Optics and Photonics (2005)
Böttger, T., Grunewald, K., Schöbinger, M., Fink, C., Risse, F., Kauczor, H., Meinzer, H., Wolf, I.: Implementation and evaluation of a new workflow for registration and segmentation of pulmonary MRI data for regional lung perfusion assessment. Phys. Med. Biol. 52(5), 1261 (2007)
Böttger, T., Kunert, T., Meinzer, H.P., Wolf, I.: Application of a new segmentation tool based on interactive simplex meshes to cardiac images and pulmonary MRI data. Acad. Radiol. 14(3), 319–329 (2007)
Boykov, Y., Veksler, O., Zabih, R.: Fast approximate energy minimization via graph cuts. IEEE Trans. Pattern Anal. Mach. Intell. 23(11), 1222–1239 (2001)
Cohen, J., Cohen, P.: Applied Multiple Regression/Correlation Analysis for the Behavioral Sciences. Lawrence Erlbaum, Hillsdale (1975)
Delingette, H.: General object reconstruction based on simplex meshes. Int. J. Comput. Vis. 32(2), 111–146 (1999)
Devaki, K., MuraliBhaskaran, V.: Study of computed tomography images of the lungs: A survey. In: 2011 International Conference on Recent Trends in Information Technology (ICRTIT), pp. 837–842. IEEE (2011)
Dice, L.R.: Measures of the amount of ecologic association between species. Ecology 26(3), 297–302 (1945)
Duda, R.O., Hart, P.E., Stork, D.G.: Pattern Classification. Wiley, New York (2000)
Fenchel, M., Requardt, M., Tomaschko, K., Kramer, U., Stauder, N.I., Naegele, T., Schlemmer, H.P., Claussen, C.D., Miller, S.: Whole-body MR angiography using a novel 32-receiving-channel MR system with surface coil technology: First clinical experience. J. Magn. Reson. Imaging 21(5), 596–603 (2005)
Gonzalez, R., Woods, R.E.: Digital Image Processing. Prentice Hall, New York (2002)
Hegenscheid, K., Kühn, J., Völzke, H., Biffar, R., Hosten, N., Puls, R.: Whole-body magnetic resonance imaging of healthy volunteers: pilot study results from the population-based ship study. Rofo 181(8), 748–759 (2009)
Heydarian, M., Kirby, M., Wheatley, A., Fenster, A., Parraga, G.: Two and three-dimensional segmentation of hyperpolarized3He magnetic resonance imaging of pulmonary gas distribution. In: Proceedings of SPIE Medical Imaging 2012, vol. 8317. International Society for Optics and Photonics (2012)
Horn, B.K.: Closed-form solution of absolute orientation using unit quaternions. J. Opt. Soc. Am. A 4(4), 629–642 (1987)
Ibanez, L., Schroeder, W., Ng, L., Cates, J.: The ITK Software Guide. Kitware Inc., Clifton Park (2003)
Ivanovska, T., Hegenscheid, K., Laqua, R., Kühn, J.P., Gläser, S., Ewert, R., Hosten, N., Puls, R., Völzke, H.: A fast and accurate automatic lung segmentation and volumetry method for mr data used in epidemiological studies. Comput. Med. Imaging Graph. 36(4), 281–293 (2012)
Jaccard, P.: The distribution of the flora in the alpine zone. 1. New Phytol. 11(2), 37–50 (1912)
Kass, M., Witkin, A., Terzopoulos, D.: Snakes: Active contour models. Int. J. Comput. Vis. 1(4), 321–331 (1988)
Kauczor, H.U.: MRI of the Lung. Springer, Berlin (2009)
Kirby, M., Heydarian, M., Svenningsen, S., Wheatley, A., McCormack, D.G., Etemad-Rezai, R., Parraga, G.: Hyperpolarized3He magnetic resonance functional imaging semiautomated segmentation. Acad. Radiol. 19(2), 141–152 (2012)
Kullberg, J., Johansson, L., Ahlström, H., Courivaud, F., Koken, P., Eggers, H., Börnert, P.: Automated assessment of whole-body adipose tissue depots from continuously moving bed MRI: a feasibility study. J. Magn. Reson. Imaging 30(1), 185–193 (2009)
Lelieveldt, B.P.F., van der Geest, R.J., Ramze Rezaee, M., Bosch, J.G., Reiber, J.H.C.: Anatomical model matching with fuzzy implicit surfaces for segmentation of thoracic volume scans. IEEE Trans. Med. Imaging 18(3), 218–230 (1999)
Lelieveldt, B.P.F., Sonka, M., Bolinger, L., Scholz, T.D., Kayser, H.W.M., van der Geest, R.J., Reiber, J.H.C.: Anatomical modeling with fuzzy implicit surface templates: application to automated localization of the heart and lungs in thoracic MR volumes. Comput. Vis. Image Underst. 80(1), 1–20 (2000)
Lichy, M.P., Mugler, B.M.W.J., Horger, W., Menzel, M.I., Anastasiadis, A., Siegmann, K., Niemeyer, T., Knigsrainer, A., Kiefer, B., Schick, F., Claussen, C.D., Schlemmer, H.P.: Magnetic resonance imaging of the body trunk using a single-slab, 3-dimensional, T2-weighted turbo-spin-echo sequence with high sampling efficiency (SPACE) for high spatial resolution imaging: initial clinical experiences. Investig. Radiol. 40(12), 754–760 (2005)
Lorensen, W.E., Cline, H.E.: Marching cubes: a high resolution 3d surface construction algorithm. In: ACM Siggraph Computer Graphics, vol. 21, pp. 163–169. ACM, New York (1987)
Lowe, D.G., et al.: Fitting parameterized three-dimensional models to images. IEEE Trans. Pattern Anal. Mach. Intell. 13(5), 441–450 (1991)
Lui, J.K., LaPrad, A.S., Parameswaran, H., Sun, Y., Albert, M.S., Lutchen, K.R.: Semiautomatic segmentation of ventilated airspaces in healthy and asthmatic subjects using hyperpolarized3He MRI. Comput. Math. Methods Med. 2013, Article ID 624683 (2013)
MacQueen, J.B.: Some methods for classification and analysis of multivariate observations. In: Proceedings of 5-th Berkeley Symposium on Mathematical Statistics and Probability, vol. 1, pp. 281–297 (1967)
Marieb, E.N., Hoehn, K.: Human Anatomy and Physiology. Pearson Education, London (2007)
Martin Bland, J., Altman, D.: Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 327(8476), 307–310 (1986)
McGraw, K.O., Wong, S.: Forming inferences about some intraclass correlation coefficients. Psychol. Methods 1(1), 30 (1996)
Memon, N.A., Mirza, A.M., Gilani, S.: Limitations of Lung Segmentation Techniques, vol. 27, chap. 76, pp. 753–766. Springer, Berlin (2009)
Middleton, I., Damper, R.I.: Segmentation of magnetic resonance images using a combination of neural networks and active contour models. Med. Eng. Phys. 26(1), 71–86 (2004)
Mills, G., Wild, J., Eberle, B., Van Beek, E.: Functional magnetic resonance imaging of the lung. Br. J. Anaesth. 91(1), 16–30 (2003)
Modersitzki, J.: Numerical Methods for Image Registration (Numerical Mathematics and Scientific Computation). Oxford university press, Oxford (2004)
Möller, H.E., Chen, X.J., Saam, B., Hagspiel, K.D., Johnson, G.A., Altes, T.A., de Lange, E.E., Kauczor, H.U.: Mri of the lungs using hyperpolarized noble gases. Magn. Reson. Med. 47(6), 1029–1051 (2002)
Osher, S., Sethian, J.A.: Fronts propagating with curvature-dependent speed: algorithms based on hamilton-jacobi formulations. J. Comput. Phys. 79(1), 12–49 (1988)
Plathow, C., Ley, S., Fink, C., Puderbach, M., Heilmann, M., Zuna, I., Kauczor, H.U.: Evaluation of chest motion and volumetry during the breathing cycle by dynamic MRI in healthy subjects: comparison with pulmonary function tests. Investig. Radiol. 39(4), 202–209 (2004)
Plathow, C., Schoebinger, M., Fink, C., Ley, S., Puderbach, M., Eichinger, M., Bock, M., Meinzer, H.P., Kauczor, H.U.: Evaluation of lung volumetry using dynamic three-dimensional magnetic resonance imaging. Investig. Radiol. 40(3), 173–179 (2005)
Pratt, J.H.: Long-continued observations on the vital capacity in health and heart disease. Am. J. Med. Sci. 164(6), 819–831 (1922)
Ray, N., Acton, S.T., Altes, T., De Lange, E.E.: Mri ventilation analysis by merging parametric active contours. In: Proceedings. 2001 International Conference on Image Processing, vol. 2, pp. 861–864. IEEE (2001)
Ray, N., Acton, S.T., Altes, T., De Lange, E.E., Brookeman, J.R.: Merging parametric active contours within homogeneous image regions for MRI-based lung segmentation. IEEE Trans. Med. Imaging 22(2), 189–199 (2003)
van Rijsbergen, C.J.: Information Retrieval. Butterworth, London (1979)
Sensakovic, W.F., Armato III, S.G.: Magnetic resonance imaging of the lung: automated segmentation methods. In: General Methods and Overviews, Lung Carcinoma and Prostate Carcinoma, pp. 219–234. Springer, Berlin (2008)
Sensakovic, W.F., Armato III, S.G., Starkey, A.: Automated lung segmentation in magnetic resonance images. In: Proc. SPIE 5747, 1776–1781 (2005)
Sensakovic, W.F., Armato III, S.G., Starkey, A., Caligiuri, P.: Automated lung segmentation of diseased and artifact-corrupted magnetic resonance sections. Med. Phys. 33, 3085 (2006)
Sluimer, I., Schilham, A., Prokop, M., van Ginneken, B.: Computer analysis of computed tomography scans of the lung: a survey. IEEE Trans. Med. Imaging 25(4), 385–405 (2006)
Sodickson, D.K., McKenzie, C.A., Ohliger, M.A., Yeh, E.N., Price, M.D.: Recent advances in image reconstruction, coil sensitivity calibration, and coil array design for smash and generalized parallel MRI. Magn. Reson. Mater. Phys., Biol. Med. 13(3), 158–163 (2002)
Soille, P.: Morphological Image Processing: Principles and Applications. Cambridge University Press, Cambridge (1999)
Sonka, M., Hlavac, V., Boyle, R.: Image Processing, Analysis, and Machine Vision. Thomson, Toronto (2008)
Tetzlaff, R., Schwarz, T., Kauczor, H.U., Meinzer, H.P., Puderbach, M., Eichinger, M.: Lung function measurement of single lungs by lung area segmentation on 2d dynamic MRI. Acad. Radiol. 17(4), 496–503 (2010)
Tokuda, J., Schmitt, M., Sun, Y., Patz, S., Tang, Y., Mountford, C.E., Hata, N., Wald, L.L., Hatabu, H.: Lung motion and volume measurement by dynamic 3d MRI using a 128-channel receiver coil. Acad. Radiol. 16(1), 22–27 (2009)
Tustison, N.J., Gee, J.C.: N4itk: Nick’s n3 itk implementation for MRI bias field correction. Insight J. (2009)
Tustison, N.J., Avants, B.B., Flors, L., Altes, T.A., de Lange, E.E., Mugler, J.P., Gee, J.C.: Ventilation-based segmentation of the lungs using hyperpolarized3He MRI. J. Magn. Reson. Imaging 34(4), 831–841 (2011)
Udupa, J.K., LaBlanc, V.R., Schmidt, H., Imielinska, C., Saha, P.K., Grevera, G.J., Zhuge, Y., Currie, L.M., Molholt, P., Jin, Y.: Methodology for evaluating image-segmentation algorithms. Med. Imaging 2002 Image Process. 4684(1), 266–277 (2002)
van Beek, E.J., Wild, J.M., Kauczor, H.U., Schreiber, W., Mugler, J.P., de Lange, E.E.: Functional MRI of the lung using hyperpolarized 3-helium gas. J. Magn. Reson. Imaging 20(4), 540–554 (2004)
Vincent, L., Soille, P.: Watersheds in digital spaces: An efficient algorithm based on immersion simulations. IEEE Trans. Pattern Anal. Mach. Intell. 13(6), 583–598 (1991)
Virgincar, R.S., Cleveland, Z.I., Sivaram Kaushik, S., Freeman, M.S., Nouls, J., Cofer, G.P., Martinez-Jimenez, S., He, M., Kraft, M., Wolber, J., et al.: Quantitative analysis of hyperpolarized 129Xe ventilation imaging in healthy volunteers and subjects with chronic obstructive pulmonary disease. NMR Biomed. 26(4), 424–435 (2012)
Warfield, S.K., Zou, K.H., Wells, W.M.: Simultaneous truth and performance level estimation (staple): an algorithm for the validation of image segmentation. IEEE Trans. Med. Imaging 23(7), 903–921 (2004)
Woodhouse, N., Wild, J.M., Paley, M.N., Fichele, S., Said, Z., Swift, A.J., van Beek, E.J.: Combined helium-3/proton magnetic resonance imaging measurement of ventilated lung volumes in smokers compared to never-smokers. J. Magn. Reson. Imaging 21(4), 365–369 (2005)
Wu, N.Y., Cheng, H.C., Ko, J.S., Cheng, Y.C., Lin, P.W., Lin, W.C., Chang, C.Y., Liou, D.M.: Magnetic resonance imaging for lung cancer detection: experience in a population of more than 10,000 healthy individuals. BMC Cancer 11(1), 242 (2011)
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Ivanovska, T., Hegenscheid, K., Laqua, R., Gläser, S., Ewert, R., Völzke, H. (2016). Lung Segmentation of MR Images: A Review. In: Linsen, L., Hamann, B., Hege, HC. (eds) Visualization in Medicine and Life Sciences III. Mathematics and Visualization. Springer, Cham. https://doi.org/10.1007/978-3-319-24523-2_1
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