Narcolepsy pp 277-282 | Cite as

Narcolepsy, Driving and Traffic Safety

  • Claire E. H. M. Donjacour
  • Monique A. J. Mets
  • Aurora J. A. E. van de Loo
  • Joris C. Verster
Chapter

Abstract

Driving performance in narcolepsy patients is often affected. This is predominantly caused by excessive daytime sleepiness and disturbed vigilance. To a lesser extent cataplexy and sleep paralysis may play a role as well.

This chapter discusses experimental studies assessing driving performance in both treated and untreated patients with narcolepsy. Driving simulator studies, on-road tests in actual traffic, and psychological test batteries show that untreated narcolepsy may significantly impair driving ability and increase the risk of becoming involved in traffic accidents. However, much more research is needed to evaluate the effects of narcolepsy treatment on driving in normal traffic, and epidemiological data on traffic accident risks should be gathered. Relatively few studies have been performed to examine effects of narcolepsy treatment on driving ability. Up to now driving improvement has been demonstrated in patients who are successfully treated with methamphetamine and modafinil. Future driving studies should examine the effect of other treatment options.

Keywords

Narcolepsy Excessive daytime sleepiness Vigilance Driving Accidents 
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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Claire E. H. M. Donjacour
    • 1
    • 2
    • 3
  • Monique A. J. Mets
    • 4
  • Aurora J. A. E. van de Loo
    • 4
  • Joris C. Verster
    • 4
    • 5
  1. 1.Sleep Centre SEIN ZwolleZwolleThe Netherlands
  2. 2.Center for Sleep-Wake Disorders and Epilepsy SEINZwolleThe Netherlands
  3. 3.Department of NeurologyLeiden University Medical CentreLeidenThe Netherlands
  4. 4.Division of PharmacologyUtrecht UniversityUtrechtThe Netherlands
  5. 5.Centre for Human PsychopharmacologySwinburne UniversityMelbourneAustralia

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