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Laser-Plasma Particle Sources for Biology and Medicine

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Progress in Ultrafast Intense Laser Science XII

Part of the book series: Springer Series in Chemical Physics ((PUILS,volume 112))

Abstract

Ultrashort, intense laser pulses can drive in plasmas small sized linear accelerators (Laser-Linac’s) of high energy elementary particles. These novel devices are facing a continuous, fast progress making them suitable alternatives to conventional linacs in many applications. Among them, cancer therapy may have by far the highest social impact at a global level. This paper is aimed at giving an updated overview of the scientific and technological effort devoted worldwide to the optimization of the laser acceleration technology in order to fulfill the clinical requirements. Here we discuss both ion and electron acceleration considering the different, challenging problems to be solved in each case. Current studies on radiobiology already in progress in many labs with the existing laser-based sources of particles are also described. The overall scenario in the field appears extremely exciting, and promises rapid, effective development.

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Acknowledgments

The authors of this Chapter are operating in the framework of the CNR High Field Photonics Unit (MD.P03.034). They acknowledge financial support from the CNR funded Italian research Network ‘ELI-Italy (Attoseconds)’, from the Italian Ministry of Health funded project GR-2009-1608935 (D.I. AgeNaS) and from the INFN funded “G-RESIST” project.

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Authors and Affiliations

  1. Intense Laser Irradiation Laboratory, Istituto Nazionale di Ottica, CNR Campus, via Moruzzi, 56124, Pisa, Italy

    Antonio Giulietti, Giancarlo Bussolino, Lorenzo Fulgentini, Petra Koester, Luca Labate & Leonida A. Gizzi

  2. INFN, Sezione di Pisa, Italy

    Luca Labate & Leonida A. Gizzi

Authors
  1. Antonio Giulietti
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  2. Giancarlo Bussolino
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  3. Lorenzo Fulgentini
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  4. Petra Koester
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  5. Luca Labate
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  6. Leonida A. Gizzi
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Corresponding author

Correspondence to Antonio Giulietti .

Editor information

Editors and Affiliations

  1. Department of Chemistry, The University of Tokyo, Tokyo, Japan

    Kaoru Yamanouchi

  2. Pulsed lasers Center, Villamayor, Salamanca, Spain

    Luis Roso

  3. Shanghai Institute of Optics and Fine Mechanics, Chinese Academy of Sciences, Shaghai, China

    Ruxin Li

  4. Tata Institute of Fundamental Research, Mumbai, India

    Deepak Mathur

  5. CEA Saclay - IRAMIS, Gif-sur-Yvette, France

    Didier Normand

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Giulietti, A., Bussolino, G., Fulgentini, L., Koester, P., Labate, L., Gizzi, L.A. (2015). Laser-Plasma Particle Sources for Biology and Medicine. In: Yamanouchi, K., Roso, L., Li, R., Mathur, D., Normand, D. (eds) Progress in Ultrafast Intense Laser Science XII. Springer Series in Chemical Physics(), vol 112. Springer, Cham. https://doi.org/10.1007/978-3-319-23657-5_8

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