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Novel Automatic Tool for Magnetic Resonance Imaging Quantification of Bone Erosion Scoring in Rheumatoid Arthritis

  • Patrizia Parascandolo
  • Lorenzo CesarioEmail author
  • Loris Vosilla
  • Francesca Barbieri
  • Marco Amedeo Cimmino
  • Gianni Viano
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9281)

Abstract

Rheumatoid arthritis (RA) is a systemic disease that affects the synovial joints. Currently, the gold standard measurement for tracking the progression of the disease involves a semi-quantitative assessment of bone erosion, bone marrow edema and synovitis, as seen in magnetic resonance images (MRI). The work presented in this paper identifies how computer automation can be used to quantify bone erosion volumes in MRI without expert and time consuming interventions. This tool is fully integrated in a computer aided diagnosis (CAD) system named RheumaSCORE (Softeco Sismat Srl). Preliminary results of qualitative and quantitative validation are presented and discussed at the end of the paper.

Keywords

Computer aided diagnosis (CAD) Erosion scoring Image processing Principal component analysis (PCA) Shape reconstruction Rheumascore Rheumatoid arthritis 

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Patrizia Parascandolo
    • 1
  • Lorenzo Cesario
    • 1
    Email author
  • Loris Vosilla
    • 2
  • Francesca Barbieri
    • 1
  • Marco Amedeo Cimmino
    • 2
  • Gianni Viano
    • 1
  1. 1.Softeco Sismat S.r.l.GenoaItaly
  2. 2.DIMI, Dipartimento di Medicina Interna, Clinica ReumatologicaUniversità degli Studi di GenovaGenoaItaly

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