Gold-Based Nanomaterials for Applications in Nanomedicine

  • Sumaira Ashraf
  • Beatriz Pelaz
  • Pablo del Pino
  • Mónica Carril
  • Alberto Escudero
  • Wolfgang J. Parak
  • Mahmoud G. Soliman
  • Qian Zhang
  • Carolina Carrillo-Carrion
Part of the Topics in Current Chemistry book series (TOPCURRCHEM, volume 370)

Abstract

In this review, an overview of the current state-of-the-art of gold-based nanomaterials (Au NPs) in medical applications is given. The unique properties of Au NPs, such as their tunable size, shape, and surface characteristics, optical properties, biocompatibility, low cytotoxicity, high stability, and multifunctionality potential, among others, make them highly attractive in many aspects of medicine. First, the preparation methods for various Au NPs including functionalization strategies for selective targeting are summarized. Second, recent progresses on their applications, ranging from the diagnostics to therapeutics are highlighted. Finally, the rapidly growing and promising field of gold-based theranostic nano-platforms is discussed. Considering the great body of existing information and the high speed of its renewal, we chose in this review to generalize the data that have been accumulated during the past few years for the most promising directions in the use of Au NPs in current medical research.

Keywords

Diagnostics Gold nanoparticles Nanomedicine Theranostics Therapeutics 

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Copyright information

© Springer International Publishing Switzerland 2016

Authors and Affiliations

  • Sumaira Ashraf
    • 1
  • Beatriz Pelaz
    • 1
  • Pablo del Pino
    • 2
  • Mónica Carril
    • 2
    • 3
  • Alberto Escudero
    • 1
    • 4
  • Wolfgang J. Parak
    • 1
    • 2
  • Mahmoud G. Soliman
    • 1
  • Qian Zhang
    • 1
  • Carolina Carrillo-Carrion
    • 1
  1. 1.Fachbereich PhysikPhilipps Universität MarburgMarburgGermany
  2. 2.CIC biomaGUNESan SebastianSpain
  3. 3.Ikerbasque, Basque Foundation for ScienceBilbaoSpain
  4. 4.Instituto de Ciencia de Materiales de SevillaCSIC-University of SevilleSevilleSpain

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