Microscopy Image Enhancement for Cost-Effective Cervical Cancer Screening

  • Joakim Lindblad
  • Ewert Bengtsson
  • Nataša Sladoje
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 9127)


We propose a simple and fast method for microscopy image enhancement and quantitatively evaluate its performance on a database containing cell images obtained from microscope setups of several levels of quality. The method utilizes an efficiently and accurately estimated relative modulation transfer function to generate images of higher quality, starting from those of lower quality, by filtering in the Fourier domain. We evaluate the method visually and based on correlation coefficient and normalized mutual information. We conclude that enhanced images exhibit high similarity, both visually and in terms of information content, with acquired high quality images. This is an important result for the development of a cost-effective screening system for cervical cancer.


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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Joakim Lindblad
    • 1
  • Ewert Bengtsson
    • 2
  • Nataša Sladoje
    • 2
    • 3
  1. 1.Faculty of Technical SciencesUniversity of Novi SadNovi SadSerbia
  2. 2.Centre for Image Analysis, Department of Information TechnologyUppsala UniversityUppsalaSweden
  3. 3.Mathematical InstituteSerbian Academy of Sciences and ArtsBelgradeSerbia

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