Imaging plays a key role in the assessment of psoriasis. However they findings are not still adequately standardized which reduces the confidence from the clinicians on his application.
Ultrasound (US) is a promising tool for the assessment of both quantification of the disease activity and the treatment responsiveness in patients with psoriasis. The continuous technological advances in this field allowed the development of equipments provided with very sensitive power Doppler (PD), which permit a sensitive detection of blood flow even in small vessels of superficial tissues such as nail and skin.
Over the past few years, videocapillaroscopy (VCP) is also generating a great interest in the assessment of microvascular changes in psoriasis representing an emergent tool for both clinical and research approaches.
This chapter provides data about the potential role of imaging, including US and VCP, in depicting both skin and nail changes in patients with psoriasis.
Psorisis Imaging Ultrasound Videocapillaroscopy Skin Nail
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Salaffi F, De Angelis R, Grassi W, MArche Pain Prevalence, INvestigation Group (MAPPING) Study. Prevalence of musculoskeletal conditions in an Italian population sample: results of a regional community-based study, I: the MAPPING study. Clin Exp Rheumatol. 2005;23:819–28.PubMedGoogle Scholar
Salomon J, Szepietowski JC, Proniewicz A. Psoriatic nails: a prospective clinical study. J Cutan Med Surg. 2003;7:317–21.PubMedCrossRefGoogle Scholar
Feldman SR, Krueger GG. Psoriasis assessment tools in clinical trials. Ann Rheum Dis. 2005;64:1165–8.CrossRefGoogle Scholar
Gupta AK, Turnbull DH, Harasiewicz KA, et al. The use of high-frequency ultrasound as a method of assessing the severity of a plaque of psoriasis. Arch Dermatol. 1996;132:658–62.PubMedCrossRefGoogle Scholar
Vaillant L, Berson M, Machet L, Callens A, Pourcelot L, Lorette G. Ultrasound imaging of psoriatic skin: a noninvasive technique to evaluate treatment of psoriasis. Int J Dermatol. 1994;33:786–90.PubMedCrossRefGoogle Scholar
El Gammal S, El Gammal C, Kaspar K, et al. Sonography of the skin at 100 MHz enables in vivo visualization of stratum corneum and viable epidermis in palmar skin and psoriatic plaques. J Invest Dermatol. 1999;113:821–9.PubMedCrossRefGoogle Scholar
El Gammal S, Auer T, Popp C, et al. Psoriasis vulgaris in 50 MHz B-scan ultrasound: characteristic features of stratum corneum, epidermis and dermis. Acta Derm Venereol Suppl (Stockh). 1994;186:173–6.Google Scholar
Serup J. Non-invasive quantification of psoriatic plaque: measurement of skin thickness with 15 MHz pulsed ultrasound. Clin Exp Dermatol. 1984;9:502–8.PubMedCrossRefGoogle Scholar
Olsen LO, Serup J. High-frequency ultrasound scan for noninvasive cross-sectional imaging of psoriasis. Acta Derm Venereol. 1993;73:185–7.PubMedGoogle Scholar
Creamer D, Allen MH, Sousa A, Poston R, Barker JN. Localization of endothelial proliferation and microvascular expansion in active plaque psoriasis. Br J Dermatol. 1997;136:859–65.PubMedCrossRefGoogle Scholar
Rosina P, Zamperetti MR, Giovannini A, Girolomoni G. Videocapillaroscopy in the differential diagnosis between psoriasis and seborrheic dermatitis of the scalp. Dermatology. 2007;214:21–4.PubMedCrossRefGoogle Scholar
Bhushan M, Moore T, Herrick AL, Griffiths CE. Nailfold video capillaroscopy in psoriasis. Br J Dermatol. 2000;142:1171–6.PubMedCrossRefGoogle Scholar
Sallì L, Raimondi F, Pappalardo A. Periungual capillaroscopy in psoriatic arthritis. Clin Ter. 1999;150:409–12.PubMedGoogle Scholar
Bull RH, Bates DO, Mortimer PS. Intravital videocapillaroscopy for the study of the microcirculation in psoriasis. Br J Dermatol. 1992;126:436–45.PubMedCrossRefGoogle Scholar
Trevisan G, Magaton Rizzi G, Dal Canton M. Psoriatic microangiopathy modifications induced by PUVA and etretinate therapy. A nail-fold capillary microscopic study. Acta Derm Venereol Suppl (Stockh). 1989;146:53–6.Google Scholar
Ribeiro CF, Siqueira EB, Holler AP, Fabrício L, Skare TL. Periungual capillaroscopy in psoriasis. An Bras Dermatol. 2012;87:550–3.PubMedCrossRefGoogle Scholar
Hegyi J, Hegyi V, Messer G, Arenberger P, Ruzicka T, Berking C. Confocal laser-scanning capillaroscopy: a novel approach to the analysis of skin capillaries in vivo. Skin Res Technol. 2009;15:476–81.PubMedCrossRefGoogle Scholar
De Angelis R, Grassi W, Cutolo M. A growing need for capillaroscopy in rheumatology. Arthritis Rheum. 2009;61:405–10.PubMedCrossRefGoogle Scholar
Cutolo M, Sulli A, Pizzorni C, Smith V. Capillaroscopy as an outcome measure for clinical trials on the peripheral vasculopathy in SSc: is it useful? Int J Rheumatol 2010;2010:pii: 784947.Google Scholar
Herrick AL, Cutolo M. Clinical implications from capillaroscopic analysis in patients with Raynaud’s phenomenon and systemic sclerosis. Arthritis Rheum. 2010;62(2):595–604.Google Scholar
Di Nardo A, Seidenari S, Giannetti A. B-scanning evaluation with image analysis of psoriatic skin. Exp Dermatol. 1992;1:121–5.PubMedCrossRefGoogle Scholar
Seidenari S. High-frequency sonography combined with image analysis: a noninvasive objective method for skin evaluation and description. Clin Dermatol. 1995;13:349–59.PubMedCrossRefGoogle Scholar
Guastalla P, Guerci VI, Fabretto A, et al. Detection of epidermal thickening in GJB2 carriers with epidermal US. Radiology. 2009;251:280–6.PubMedCrossRefGoogle Scholar
Gutierrez M, De Angelis R, Bernardini ML, et al. Clinical, power Doppler sonography and histological assessment of the psoriatic plaque: short-term monitoring in patients treated with etanercept. Br J Dermatol. 2011;164:33–7.PubMedCrossRefGoogle Scholar
Gutierrez M, Di Geso L, Salaffi F, et al. Development of a preliminary US power Doppler composite score for monitoring treatment in PsA. Rheumatology. 2012;51:1261–8.PubMedCrossRefGoogle Scholar
Hern S, Mortimer OS. In vivo quantification of microvessels in clinically univolved psoriatic skin and in normal skin. Br J Dermatol. 2007;156:1224–9.PubMedCrossRefGoogle Scholar
Espinoza LR, Vasey FB, Espinoza GG, Bocanegra TS, Germain BF. Vascular changes in psoriatic synovium. A light and electron microscopy study. Arthritis Rheum. 1982;25:677–84.PubMedCrossRefGoogle Scholar
Bhusman M, Moore T, Herrick A, Griffiths CEM. Naildfold video capillaroscopy in psoriasis. Br J Dermatol. 2000;142:1171–6.CrossRefGoogle Scholar
Bartosinska J, Chodorowska G. Original proposal of capillaroscopic images classification in psoriasis vulgaris and psoriatic arthritis. Adv Dermatol Allergol. 2009;26:17.Google Scholar
Musumeci ML, Lacarrubba F, Fusto CM, Micali G. Combined clinical, capillaroscopic and ultrasound evaluation during treatment of plaque psoriasis with oral cyclosporine. Int J Immunopathol Pharmacol. 2013;26:1027–33.PubMedGoogle Scholar
Stinco G, Buligan C, Maione V, Valent F, Patrone P. Videocapillaroscopic findings in the microcirculation of the psoriatic plaque during etanercept therapy. Clin Exp Dermatol. 2013;38:633–7.PubMedCrossRefGoogle Scholar
Rosina P, Giovannini A, Gisondi P, Girolomoni G. Microcirculatory modifications of psoriatic lesions during topical therapy. Skin Res Technol. 2009;15:135–8.PubMedCrossRefGoogle Scholar
Stinco G, Lautieri S, Piccirillo F, Valent F, Patrone P. Response of cutaneous microcirculation to treatment with mometasone furoate in patients with psoriasis. Clin Exp Dermatol. 2009;34:915–9.PubMedCrossRefGoogle Scholar