Concentrated photoactivation: focusing light through scattering

  • A. Gabriel
  • J. Machado
  • R. Gomes
  • J. M. P. Coelho
  • C. O. Silva
  • C. P. Reis
  • J. P. Santos
  • P. Vieira
Part of the IFMBE Proceedings book series (IFMBE, volume 51)

Abstract

Light has long being used in medicine; however, the high scattering of biological tissues always hindered its use. The aim of this work is the development of methodologies to focus light inside biological tissues. Geant4/GAMOS Monte Carlo platform was used to simulate the possibility of parameterize the time delay of multiple sources of external light, offset in time, as a function of the interest region position in order to create constructive interferences in a breast sample. A computational model was implemented and the platform was configured in order to perform these simulations. Preliminary results using a single light source were performed. It was concluded that scattering in adipose tissue is very high which is consistent with previous studies.

Keywords

Biological tissues phantom Scattering Geant4 GAMOS Near-infrared spectroscopy 

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Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • A. Gabriel
    • 1
  • J. Machado
    • 1
  • R. Gomes
    • 3
  • J. M. P. Coelho
    • 2
    • 3
  • C. O. Silva
    • 4
  • C. P. Reis
    • 4
  • J. P. Santos
    • 1
  • P. Vieira
    • 1
  1. 1.LIBPhys-UNL, Departamento de Física, Faculdade de Ciências e TecnologiaUniversidade Nova de LisboaMonte da CaparicaPortugal
  2. 2.Laboratório de Óptica, Lasers e Sistemas, Faculdade de CiênciasUniversidade de LisboaLisboaPortugal
  3. 3.Instituto de Biofísica e Engenharia Biomédica, Faculdade de CiênciasUniversidade de LisboaLisboaPortugal
  4. 4.CBiOS - Centre for Research in Biosciences & Health TechnologiesUniversidade LusófonaLisboaPortugal

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