CIDANE: Comprehensive Isoform Discovery and Abundance Estimation
High-throughput sequencing of cellular RNA (RNA-seq) allows to assess the set of all RNA molecules, the transcriptome, produced by a cell at a high resolution, under various conditions. The assembly of short sequencing reads to full-length transcripts, however, poses profound challenges to bioinformatics tools.
KeywordsInteger Linear Programming Abundance Estimation Result Optimization Problem Lasso Regression Regularization Path
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