Urological Cancer Management pp 15-28 | Cite as
Symptoms, Signs, Clinical Examination, Primary Diagnostic Methods and Disease Extension Investigations
Abstract
Localized PC is generally an asymptomatic disease. It may sometimes present with lower urinary tract symptoms (LUTS). Locally advanced disease may also be asymptomatic, but with time it will more likely present with urinary obstruction, urinary infections, haematuria, impotence, tenesmus, obstructive uropathy with uraemia, etc. Haematospermia is a rare symptom of PC, found in only 0.5 % of cases; but its presence should prompt screening for PC in selected patients since it has been associated with a PC diagnosis in 13.7 % of patients [1–3]. Metastatic disease generally present with complications. These may be local in keeping with locally advanced disease, distant (back pain, spontaneous fracture, paraplegia, obstructive jaundice caused by massive para-aortic and para-caval lymph nodes compressing the common bile duct) or systemic when the general health is affected by anorexia, loss of weight and anaemia.
Keywords
Lower Urinary Tract Symptom Gleason Score Prostatic Biopsy Prostatic Intraepithelial Neoplasia Positive CoreReferences
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