THiMED: Time in Hierarchical Model Extraction and Design
We describe our approach to modeling timing of cell signaling systems in which existing information about the system spans from detailed mechanistic knowledge to much coarser observations about cause and effect. The results for several models emphasize the fact that the selection of timing implementation can have both qualitative and quantitative effects on the model’s transient behavior and its steady state.
Keywordstiming cell signaling stochastic model delay
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