Atrioventricular Septal Defect (Transitional Form)

  • Hakimeh Sadeghian
  • Zahra Savand-Roomi


A 57-year-old woman presented with dyspnea on exertion (functional class II) of 1-year duration. She had a history of breast ductal invasive carcinoma 2 years previously and had undergone mastectomy and chemotherapy. She was nulliparous. Physical examination revealed a holosystolic murmur at the apex and the lower left sternal border. Electrocardiography showed normal sinus rhythm and left axis deviation.

Supplementary material

Video 22.1

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  1. 7.
    Baumgartner H, Bonhoeffer P, De Groot NM, de Haan F, Deanfield JE, Galie N, et al. ESC guidelines for the management of grown-up congenital heart disease (new version 2010). Eur Heart J. 2010;31(23):2915–57 [Practice Guideline].CrossRefPubMedGoogle Scholar
  2. 54.
    Seguela PE, Brosset P, Acar P. Isolated cleft of the posterior mitral valve leaflet assessed by real-time 3D echocardiography. Arch Cardiovasc Dis. 2011;104(5):365–6.CrossRefPubMedGoogle Scholar
  3. 55.
    Furukawa N, Aboud A, Hakim-Meibodi K, Gummert J. Mitral regurgitation caused by an isolated mitral leaflet cleft. Ann Thorac Surg. 2011;91(6):1984–6.CrossRefPubMedGoogle Scholar

Copyright information

© Springer International Publishing Switzerland 2015

Authors and Affiliations

  • Hakimeh Sadeghian
    • 1
  • Zahra Savand-Roomi
    • 2
  1. 1.Department of EchocardiographyTehran University of Medical Sciences Tehran Heart CentreTehranIran
  2. 2.Department of EchocardiographyKowsar HospitalShirazIran

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