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Programming Living Machines: The Case Study of Escherichia Coli

  • Jole Costanza
  • Luca Zammataro
  • Giuseppe Nicosia
Part of the Lecture Notes in Computer Science book series (LNCS, volume 8608)

Abstract

In 1952, Turing outlined computational processes in the morphogenesis [8], thus thinking of the biological evolution of an organism as a consequence of the computation that it can perform. Following Turing’s idea on morphogenesis, many biological processes have been recently analysed from a computational standpoint. In 1995, Bray [2] argued that a single protein is a computational or information carrying element, being able to convert input signals into an output signal. Evolution had already been associated with computation many years before, by von Neumann and Burks [9], who constructed a self-replicating cellular automaton with the aim of developing synthetic models of a living organism. Starting from this concept, in this work we propose a relation between computation and metabolism.

Keywords

Pareto Front Turing Machine Flux Balance Analysis Molecular Machine Pareto Point 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer International Publishing Switzerland 2014

Authors and Affiliations

  • Jole Costanza
    • 1
  • Luca Zammataro
    • 1
  • Giuseppe Nicosia
    • 2
  1. 1.Italian Institute of TechnologyMilanItaly
  2. 2.Department of Mathematics and Computer ScienceUniversity of CataniaItaly

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